Pilot-scale production of butanol by Clostridium beijerinckii BA101 using a low-cost fermentation medium based on corn steep water

Parekh, Manish; Formanek, Joseph; Blaschek, Hans P.

doi:10.1007/s002530051375

Cited by 83 publications

(41 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2 Total C 6 and C 5 sugars yield from different pretreatment methods. C 6 and C 5 sugars as presented in this figure mainly consist of glucose and xylose, respectively, and based on data reported in several previous studies as: Hydrothermal (Feng et al 2014;Lloyd and Wyman 2005;Mosier et al 2005;Shen and Wyman 2011); Steam explosion (Bondesson et al 2013;Liu et al 2013a, b;Varga et al 2004); Sulfuric acid (Avci et al 2013a;Feng et al 2014;Lloyd and Wyman 2005;Qin et al 2012;Shen and Wyman 2011); Phosphoric acid (Avci et al 2013b); Oxalic acid (Feng et al 2014;Mtui 2012;Qin et al 2012); Ammonia (Feng et al 2014;Kim et al 2003;Kim and Lee 2005b;Teymouri et al 2005;; Sodium hydroxide (Feng et al 2014); Ionic liquid Uppugundla et al 2014); Methylamine (Feng et al 2014); Biphasic (unpublished data) Lin and Blaschek 1983;Mu et al 2011;Parekh and Formanek 1999;Qureshi et al 2007Qureshi et al , 2010b; Wang and Chen 2011;Zhang et al 2009). A review by Li et al (2014) identified different nutrients required by Clostridium sp.…”

Section: Feedstocks For Abe Fermentationmentioning

confidence: 95%

Microbial inhibitors: formation and effects on acetone-butanol-ethanol fermentation of lignocellulosic biomass

Baral

Shah

2014

Appl Microbiol Biotechnol

144

View full text Add to dashboard Cite

Biobutanol is a promising biofuel due to the close resemblance of its fuel properties to gasoline, and it is produced via acetone-butanol-ethanol (ABE) fermentation using Clostridium species. However, lignin in the crystalline structure of the lignin-cellulose-hemicellulose biomass complex is not readily consumed by the Clostridium; thus, pretreatment is required to degrade this complex. During pretreatment, some fractions of cellulose and hemicellulose are converted into fermentable sugars, which are further converted to ABE. However, a major setback resulting from common pretreatment processes is the formation of sugar and lignin degradation compounds, including weak acids, furan derivatives, and phenolic compounds, which have inhibitory effects on the Clostridium. In addition, butanol concentration above 13 g/L in the fermentation broth is itself toxic to most Clostridium strain(s). This review summarizes the current state-of-the-art knowledge on the formation of microbial inhibitors during the most common lignocellulosic biomass pretreatment processes. Metabolic effects of inhibitors and their impacts on ABE production, as well as potential solutions for reducing inhibitor formation, such as optimizing pretreatment process parameters, using inhibitor tolerant strain(s) with high butanol yield ability, continuously recovering butanol during ABE fermentation, and adopting consolidated bioprocessing, are also discussed.

show abstract

Section: Feedstocks For Abe Fermentationmentioning

confidence: 95%

Microbial inhibitors: formation and effects on acetone-butanol-ethanol fermentation of lignocellulosic biomass

Baral

Shah

2014

Appl Microbiol Biotechnol

144

View full text Add to dashboard Cite

show abstract

“…Studies with C. beijerinckii BA101 suggest that the developed strain is stable and can be used in a commercial fermentation process for producing butanol from glucose and cornstarch [5,6]. However, like other butanol-producing microorganisms, butanol is toxic to C. beijerinckii BA101.…”

Section: Introductionmentioning

confidence: 99%

Improving performance of a gas stripping-based recovery system to remove butanol from Clostridium beijerinckii fermentation

Ezeji

Karcher

Qureshi

et al. 2005

Bioprocess Biosyst Eng

149

View full text Add to dashboard Cite

The effect of factors such as gas recycle rate, bubble size, presence of acetone, and ethanol in the solution/broth were investigated in order to remove butanol from model solution or fermentation broth (also called acetone butanol ethanol or ABE or solvents). Butanol (8 g L(-1), model solution, Fig. 2) stripping rate was found to be proportional to the gas recycle rate. In the bubble size range attempted (< 0.5 and 0.5-5.0 mm), the bubble size did not have any effect on butanol removal rate (Fig. 3, model solution). In Clostridium beijerinckii fermentation, ABE productivity was reduced from 0.47 g L(-1) h(-1) to 0.25 g L(-1) h(-1) when smaller (< 0.5 mm) bubble size was used to remove ABE (Fig. 4, results reported as butanol/ABE concentration). The productivity was reduced as a result of addition of an excessive amount of antifoam used to inhibit the production of foam caused by the smaller bubbles. This suggested that the fermentation was negatively affected by antifoam.

show abstract

“…The anaerobic medium was maintained by oxygen free nitrogen. Parekh et al [72] reported the use of a pilot-scale of 200 litres using corn steep liquor as the raw material, obtaining 17.8 g/L of butanol. The same size of bioreactor was used by Lee et al [59].…”

Section: Bioreactors For Biobutanol Productionmentioning

confidence: 99%

Recent advances on biobutanol production

Visioli

Enzweiler

Kuhn

et al. 2014

Sustain Chem Process

View full text Add to dashboard Cite

Recent studies have shown that butanol is a potential gasoline replacement that can also be blended in significant quantities with conventional diesel fuel. However, biotechnological production of butanol has some challenges such as low butanol titer, high cost feedstocks and product inhibition. The present work reviewed the technical and economic feasibility of the main technologies available to produce biobutanol. The latest studies integrating continuous fermentation processes with efficient product recovery and the use of mathematical models as tools for process scale-up, optimization and control are presented.

show abstract

Pilot-scale production of butanol by Clostridium beijerinckii BA101 using a low-cost fermentation medium based on corn steep water

Cited by 83 publications

References 11 publications

Microbial inhibitors: formation and effects on acetone-butanol-ethanol fermentation of lignocellulosic biomass

Microbial inhibitors: formation and effects on acetone-butanol-ethanol fermentation of lignocellulosic biomass

Improving performance of a gas stripping-based recovery system to remove butanol from Clostridium beijerinckii fermentation

Recent advances on biobutanol production

Contact Info

Product

Resources

About