Pimozide Treatment in Disruptive Severely Retarded Patients

White, Tony; Aman, Michael G.

doi:10.3109/00048678509158820

Cited by 22 publications

(7 citation statements)

References 5 publications

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“…The authors' report of internal consistency is high (mean subscale alpha coefficient of .90), inter-rater reliability is moderate to high (mean r l .63), and test-retest reliability ranges from .96 to .99 for each of the subscales (Aman, Singh, Stewart, & Field, 1985). Criterion group validity and the validity of the instrument in relation to other methods of assessing behaviour are also good (Aman & Singh, 1986) and the ABC has proved to be a sensitive measure of drug effects, including effects of stimulant and antipsychotic drugs (Aman & Singh, 1982 ;White & Aman, 1985).…”

Section: Assessmentsmentioning

confidence: 99%

Behavioural Treatment for Sleep Problems in Children with Severe Learning Disabilities and Challenging Daytime Behaviour: Effect on Daytime Behaviour

Wiggs

Stores

1999

Child Psychology Psychiatry

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The study aimed to investigate a group of children with severe learning disabilities, challenging daytime behaviour, and severe sleep problems to see if successful behavioural treatment of the children's sleep problems resulted in reduced daytime challenging behaviour as reported by mothers and teachers. A randomised controlled trial of behavioural interventions for the children's sleep problems was conducted (N = 30). The intervention group received an individually tailored behavioural programme and were supported by telephone calls from the therapist. Baseline assessments of the children's behaviour were made using the Aberrant Behavior Checklist and were repeated 1 month and 3 months after the start of intervention. There were no behavioural changes that were specific to children in the treatment group. However, improvements in some behaviours were seen in both the intervention and the control group at the 1-month and 3-month assessments and there was agreement between mothers' and teachers' reports for many of these changes. The results suggest that nonspecific effects of participating in the study (including an increased sleep duration, which was seen in both groups), rather than resolution of sleep problem per se, may have a beneficial effect on child behaviour and these factors need to be identified for therapeutic use.

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Section: Assessmentsmentioning

confidence: 99%

Behavioural Treatment for Sleep Problems in Children with Severe Learning Disabilities and Challenging Daytime Behaviour: Effect on Daytime Behaviour

Wiggs

Stores

1999

Child Psychology Psychiatry

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“…Three studies included only adults with intellectual disabilities: a double-blind placebo controlled crossover trial 32 and a single-case experimental reversal design of pharmacotherapy, 33 as well as a single-case experimental reversal design of a psychological intervention. 34 Two studies included children and young people: a randomised trial of pharmacotherapy by White and Aman 35 and a single-case study of a psychological intervention for a 13-year-old girl. 36 …”

Section: Resultsmentioning

confidence: 99%

“…White and Aman 35 evaluated the use of pimozide on maladaptive behaviours and hyperactivity, in young people and adults with moderate to profound intellectual disabilities. Following a 4-week baseline, the eight participants received two 4-week treatments with either pimozide, in a dosage of 0.12 mg/kg/day, or placebo, with a 1-week washout period between intervention phases.…”

Section: Resultsmentioning

confidence: 99%

Interventions for mental health problems in children and adults with severe intellectual disabilities: a systematic review

et al. 2018

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ObjectiveMental health problems are more prevalent in people with than without intellectual disabilities, yet treatment options have received little attention. The aim of this study was to identify and evaluate the effectiveness of pharmacological and psychological interventions in the treatment of mental health problems in children and adults with severe and profound intellectual disabilities, given their difficulties in accessing standard mental health interventions, particularly talking therapies, and difficulties reporting drug side effects.DesignA systematic review using electronic searches of PsycINFO, PsycTESTS, EMBASE, MEDLINE, CINAHL, ERIC, ASSIA, Science Citation Index, Social Science Citation Index and CENTRAL was conducted to identify eligible intervention studies. Study selection, data extraction and quality appraisal were performed by two independent reviewers.ParticipantsStudy samples included at least 70% children and/or adults with severe or profound intellectual disabilities or reported the outcomes of this subpopulation separate from participants with other levels of intellectual disabilities.InterventionsEligible intervention studies evaluated a psychological or pharmacological intervention using a control condition or pre-post design.OutcomesSymptom severity, frequency or other quantitative dimension (e.g., impact), as assessed with standardised measures of mental health problems.ResultsWe retrieved 41 232 records, reviewed 573 full-text articles and identified five studies eligible for inclusion: three studies evaluating pharmacological interventions, and two studies evaluating psychological interventions. Study designs ranged from double-blind placebo controlled crossover trials to single-case experimental reversal designs. Quality appraisals of this very limited literature base revealed good experimental control, poor reporting standards and a lack of follow-up data.ConclusionsMental ill health requires vigorous treatment, yet the current evidence base is too limited to identify with precision effective treatments specifically for children or adults with severe and profound intellectual disabilities. Clinicians therefore must work on the basis of general population evidence, while researchers work to generate more precise evidence for people with severe and profound intellectual disabilities.PROSPERO registration numberCRD 42015024469.

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“…Чеклиста аберантног понашања је настала са циљем евалуације ефеката третмана код особа са интелектуалном ометеношћу, па се стога уочава велики број истраживања у којима се прати улога медикаментозне терапије у третирању неприхватљивих понашања. (35,36,37,38,39,40) Чеклиста аберантног понашања је Ликертовог типа и њом се у распону од 0 -нема бихевиоралних проблема до 3озбиљни проблеми у понашању, про це њује присуство маладаптивних облика пона шања код деце и одраслих са интеле ктуа лном ометеношћу. (9) Састоји се од 58 ајтема распоређених у пет супскала: ра здра жљивост, летаргија, стереотипи, хи пера ктивност и неприкладан говор.…”

Section: преглед инструмената за процену проблема у понашању код особunclassified

Assessment of maladaptive behavior in individuals suffering with severe intellectual disability

Đorđević¹,

Konsuelo-Talijan²

2014

Zdravstvena zaštita

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Најчешћи облици маладаптивног пона шања код особа са тежим облицима инте лектуалне ометености су агресивно, де структивно и аутоагресивно понашање. Циљ овог рада је да се увидом у досту пну литературу укаже на разли чите могу ћности процене проблема у пона шању код особа са тежим облицима интеле ктуалне ометености. Претрагом електронске базе података Конзорцијума библиотеке Србије за обједи њену набавку-КоБСОН, прикупљени су и анализирани радови у којима је обрађивана тема процене проблема у понашању код особа са тежим облицима интелектуалне ометености. Анализом доступних радова уочено је да многи аутори истичу значај бихевиоралног приступа у процени и третману проблема у понашању код особа са тежим облицима интелектуалне ометености. Поред често коришћених индиректних, истраживачи указују и на значај дескриптивних и експе рименталних метода у процени. У раду је приказано седам инструмената за процену проблема у понашању. Кључне речи: бихевиорални приступ, инте лектуална ометеност, проблеми у по на шању, процена.

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Pimozide Treatment in Disruptive Severely Retarded Patients

Cited by 22 publications

References 5 publications

Behavioural Treatment for Sleep Problems in Children with Severe Learning Disabilities and Challenging Daytime Behaviour: Effect on Daytime Behaviour

Behavioural Treatment for Sleep Problems in Children with Severe Learning Disabilities and Challenging Daytime Behaviour: Effect on Daytime Behaviour

Interventions for mental health problems in children and adults with severe intellectual disabilities: a systematic review

Assessment of maladaptive behavior in individuals suffering with severe intellectual disability

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