Pimpinella anisum seeds essential oil from Lesvos island: Effect of hydrodistillation time, comparison of its aromatic profile with other samples of the Greek market. Safe use

Anastasopoulou, Eleni; Graikou, Konstantia; Ganos, Christos; Calapai, Gioacchino; Chinou, İoanna

doi:10.1016/j.fct.2019.110875

Cited by 30 publications

(19 citation statements)

References 16 publications

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“…However, special attention should be given prior to recommending the use of MAPs in human diet, since, in several occasions, the intake of high doses of secondary metabolites and potentially harmful substances (e.g., heavy metals and anti-nutritional factors) may cause severe toxicity and adverse health effects [25][26][27][28]. Therefore, further research is needed to evaluate possible toxic effects and establish recommended daily allowance (RDA) levels, especially for people with medical conditions [29][30][31].…”

Section: Introductionmentioning

confidence: 99%

Profiling of Essential Oils Components and Polyphenols for Their Antioxidant Activity of Medicinal and Aromatic Plants Grown in Different Environmental Conditions

et al. 2020

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In the present study, the yield, the chemical composition, and the antioxidant activities of the essential oils (EOs) of eight medicinal and aromatic plants (MAPs) cultivated under two environmental conditions characterized by a different altitude (namely mountainous and plain) were evaluated. Cultivation at different environmental conditions resulted in significant differences in the chemical composition and antioxidant activity for most of the studied species. In particular, high altitudes resulted in increased phenolic compounds’ content and antioxidant activity for artemisia plants, while specific parameters increased in the case of spearmint (total phenols) and rosemary (flavonoids). In contrast, in pelargonium, all the tested parameters were positively affected in the plain area, whereas, for laurel and sage, only flavanols remained unaffected. EO yield in mountainous pelargonium and spearmint decreased while, in mountainous laurel, pelargonium and spearmint increased when compared to plain areas. In addition, the major EO constituents’ content for most of the species were affected by environmental conditions. The 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) and ferric reducing antioxidant power (FRAP) were variably correlated with total phenols, flavonoids, and flavanols, depending on the species and the altitude. Lastly, in limited cases, antioxidant activity (DPPH or FRAP values) was positively correlated with some EO components (e.g., borneol and β-pinene in artemisia and laurel plants grown in the plain, respectively, or 1,8-cineole in mountainous grown verbena plants). In conclusion, environmental conditions (altitude) affected antioxidants’ content and EO yield and composition of the studied MAPs. These findings can be used to introduce cultivation of MAPs in specific ecosystems for the production of high added value products.

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Section: Introductionmentioning

confidence: 99%

Profiling of Essential Oils Components and Polyphenols for Their Antioxidant Activity of Medicinal and Aromatic Plants Grown in Different Environmental Conditions

et al. 2020

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“…Ketones 5h , 5s , and 5ae were reduced to the corresponding alcohols with NaBH 4 for successful isolation from the otherwise inseparable byproduct (triphenylpyridine). We also obtained 5p , a naturally occurring essential oil in Aniseed, and 5v , a metabolite, in high yields . It is noteworthy to mention that 5af , a derivative of antiarrhythmic drug Mexiletine, was also prepared in 24% yield using this method.…”

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confidence: 99%

Nickel-Catalyzed Cross-Coupling of Alkyl Carboxylic Acid Derivatives with Pyridinium Salts via C–N Bond Cleavage

et al. 2020

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The electrophile−electrophile cross-coupling of carboxylic acid derivatives and alkylpyridinium salts via C−N bond cleavage is developed. The method is distinguished by its simplicity and steers us through a variety of functionalized ketones in good to excellent yields. Besides acid chlorides, carboxylic acids were also employed as acylating agents, which enabled us to incorporate acid-sensitive functional groups such as MOM, BOC, and acetal. Control experiments with TEMPO revealed a radical pathway.

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“…Pimpinella anisum L. (commonly known as aniseed) used in this work is one of the oldest known medicinal plants that belongs to the family Apiaceae and was initially cultivated in Egypt and later in Greece, Rome and the Middle East. This is a very versatile plant as several derivatives of aniseed plant (fruits, seeds and essential oil) are widely used in the food and beverage industries as a flavouring‐agent and natural preservative (Anastasopoulou et al ., 2020). Among them, essential oil extracted from aniseed seeds has attracted the highest interest and several studies have been carried out and particularly the effect of the hydro‐distillation process on the composition of the extracted essential oil was studied (Zayed et al ., 2020).…”

Section: Introductionmentioning

confidence: 99%

Isolation of antimicrobial compounds from aniseed and techno‐economic feasibility report for industrial‐scale application

Κουτίνας

2022

Int J of Food Sci Tech

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Summary This work evaluates the antimicrobial activity of the fractionated aqueous extract obtained from the aerial parts of aniseed. Fifteen fractions were collected by column chromatography using ethanol and water as mobile phases. All fractions were tested as potential antimicrobial agents against three common food‐spoilage microorganisms: a yeast (Saccharomyces cerevisiae), a mold (Aspergillus awamori) and a bacterium (Lactobacillus delbrueckii subsp. bulgaricus). Fraction 2 exhibited the highest antimicrobial activity in both types of susceptibility test, and therefore, it was further studied for the identification of bioactive compounds. GC‐MS analysis of Fraction 2 revealed the presence of threo‐Anethole glycol. Based on laboratory‐scale experiments, a process flowsheet for potential industrial‐scale application is proposed combined with a techno‐economic feasibility report. Fraction 2 with the detected compound threo‐Anethole glycol showed promising results encouraging the attempts for industrial‐scale application of antimicrobial compounds produced from aniseed.

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Pimpinella anisum seeds essential oil from Lesvos island: Effect of hydrodistillation time, comparison of its aromatic profile with other samples of the Greek market. Safe use

Cited by 30 publications

References 16 publications

Profiling of Essential Oils Components and Polyphenols for Their Antioxidant Activity of Medicinal and Aromatic Plants Grown in Different Environmental Conditions

Profiling of Essential Oils Components and Polyphenols for Their Antioxidant Activity of Medicinal and Aromatic Plants Grown in Different Environmental Conditions

Nickel-Catalyzed Cross-Coupling of Alkyl Carboxylic Acid Derivatives with Pyridinium Salts via C–N Bond Cleavage

Isolation of antimicrobial compounds from aniseed and techno‐economic feasibility report for industrial‐scale application

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