PIN170 The NOVEL Coronavirus Disease (COVID-19): Impacts on TESTS and Hospitalizations Performance in a Health PLAN in Brazil

Abstract

comprehensive epidemiological understanding of SARS-COV-2 (COVID-19) symptoms, clustering and resolution; (2) provide data on the impact of both infection and the pandemic on people's lives; and (3) offer a full understanding of treatment benefit in studies designed to treat or vaccinate against COVID-19. Methods: A review of the literature (March 2020) used COVID-19 and signs, symptoms and impacts search terms. A preliminary conceptual model was developed and novel PRO items were drafted. A review of social media (June 2020) informed an updated conceptual model and PRO items. Joint concept elicitation-cognitive interviews were completed with people who had experienced COVID-19 (June-July 2020). Results: The literature (25 articles), social media (.200 million mentions) and interviews (n=10) highlighted a heterogenous list of signs, symptoms and impacts of COVID-19 infections, and a broad list of impacts of the pandemic in general. Novel PROs are intended to be comprehensive, so the incidence and severity of 42 signs and symptoms are measured. Fifteen additional items ask about the impact of infection (physical, emotional and social) and 18 about the impact of the pandemic. The PRO is adaptive (modular) to allow administration to people with and without COVID-19 infection. Weekly-and daily-recall versions were tested in cognitive interviews resulting in adjustments to ensure understandability. Conclusions: Novel content-valid PROs have been developed to measure the signs, symptoms and impacts of COVID-19 pandemic and infection. These are currently being employed in a large longitudinal study to evaluate their psychometric measurement properties.

Economic Burden of COVID-19: A Systematic Review

“…81% of services had cared for patients with suspected or confirmed COVID-19, or both • 48% of survey respondents reported shortages of PPE, 40% shortages of staff, 24% shortages of medicines, and 14% shortages of other equipment • Palliative care services were often overwhelmed. Highest shortages were reported for PPE and staff Falah 2021 23 Arab countries Determined which Arab countries excelled at the detection, containment, and at the treatment stages of COVID-19 • UAE and Bahrain conducted the highest in the number of COVID-19 tests per death which indicated widespread testing and assessment of community transmission • Arab countries show less deaths per million and less doubling time for confirmed deaths compared to most OCED countries such as Italy, Spain, USA, UK, France and Canada • Countries such as Egypt, Sudan, Syria, and Tunisia with a high prevalence of diabetes and cardiovascular disease have higher COVID-19 case fatality rates Busch 2020 24 Brazil Conducted a retrospective non-interventional study of 41,640 patients using population-based health administrative databases • Outcomes of this study were the number of prior authorizations to tests and hospitalizations during two periods of 90 days, before (P1) and after (P2) the first registered case of COVID-19 • During the 180-day study period- 21,583 patients underwent to tests, 15,018 in P1 and 6565 in P2, a reduction of 56.3% and 3316 hospitalizations occurred which was a reduction of 39.5% Hashmi 2020 25 Pakistan A single center retrospective study was conducted to quantify losses due to postponement of elective surgeries and extra cost for procurement of PPEs and to quantify the total inpatient costs during COVID • 625 patients were admitted during study period • During Covid there was a: o 50% reduction in patients’ admissions o 43.15% reduction of emergency procedures o 55.7% decrease in revenue due to postponement of elective work Heppner 2020 26 US Conducted a review of all visits in a Louisville, Kentucky level 1 trauma center from February to May in 2020 in comparison to same time in the previous year • A total of 34,213 ED visits occurred during the study periods (18,471 in 2019 and 15,742 in 2020) • In 2020, patients were less likely to be female and more likely to arrive by ambulance • The daily mean visits per day in the ED in 2019 was 153.9 (SD = 16.3) which was higher than 2020ʹs daily census average of 129.9 (SD = 25.1) • The mean difference between the two groups of 24 visits per day (95% CI: 18.3–29.7) was statistically significant, p < 0.001 Shin 2020 27 Japan …”