Pincer ligands based on α-amino acids: V. New generation chiral receptors for the recognition of amino acid enantiomers in aqueous environment

Abstract

Selective recognition of enantiomers of amino acids valine, methionine, phenylalanine, serine, and tyrosine by a binuclear copper complex with an azomethine obtained from 2,6-diformyl-4-methylphenol and L-valine was studied by means of spectrophotometry. The binding constants of individual enentiomers were estimated for valine, phenylalanine, methionine, serine, and tyrosine, and the enantioselectivity factors were evaluated. The isomers of serine and tyrosine (with respect to the fi rst stage) were recognized with a considerable enantioselectivity (1.34 and 5.46 respectively), whereas the binding constants of valine and phenylalanine enantiomers are virtually indistinguishable.

Fluorescent/Colorimetric Dual-Mode Discriminating Gln and Val Enantiomers Based on Carbon Dots

“…In the fluorescent mode, (F 550 /F 475 ) D /(F 550 /F 475 ) L for Gln is 5.29 and (F 550 /F 475 ) L /(F 550 /F 475 ) D for Val is 4.13. Compared with previous works, in both fluorescent and colorimetric modes, this probe all shows comparable or better chiral recognition ability. – …”