Pincer nail in a lupus patient

Azevedo, T H V; Neiva, Cláudia Lopes Santoro; Consoli, Rita; Couto, A.C.D.; Dias, A F M P; Souza, Eduardo José do Rosário e

doi:10.1177/0961203317694258

Cited by 4 publications

(8 citation statements)

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“…In another case, reported by Twigg et al [14], the patient developed pincer nail deformity 12 years after the diagnosis of SLE, and there were no other cutaneous manifestations of SLE. Recently Azevedo et al reported an SLE patient with class V lupus nephritis who had classic cutaneous, musculoskeletal and psychiatric features of SLE with pincer nail deformity [15]. Interestingly, our patient did not develop any specific cutaneous manifestations of SLE or any signs of hepatitis, despite the high Dermatology Review/Przegląd Dermatologiczny 2017/3 występowania objawu Raynauda i owrzodzeń błony śluzowej jamy ustnej u pacjentów z SLE ze zmianami paznokciowymi [19].…”

Section: Discussionmentioning

confidence: 61%

“…Ostatnio Azevedo i wsp. przedstawili pacjenta z SLE oraz nefropatią toczniową klasy V, u którego stwierdzono klasyczne skórne, mięśniowo-szkieletowe i psychiczne zaburzenia typowe dla SLE, a także paznokcie pincetowate [15]. Co ciekawe, u naszej pacjentki nie wystąpiły żadne swoiste objawy skórne SLE ani objawy zapalenia wątroby pomimo bardzo wysokiego miana przeciwciał ANA, anty-dsDNA oraz dodatnich przeciwciał anty-AMA-M2 i przeciwciał przeciwko nukleosomom.…”

Section: Discussionunclassified

“…β-adrenolityków (praktolol, acebutolol) [6][7][8][9][10][11][12]. Przypadki paznokci pincetowatych w przebiegu tocznia rumieniowatego układowego (systemic lupus erythematosus -SLE) opisano w latach 2005 [13] i 2016 [14] oraz ostatnio -w styczniu 2017 r. [15], jednak według naszej wiedzy w piśmiennictwie nie ma doniesień dotyczących występowania paznokci pincetowatych jako jedynego skórnego objawu SLE.…”

Section: Case Reportunclassified

“…β-blockers such as practolol and acebutolol, can lead to pincer nail deformity [6][7][8][9][10][11][12]. Pincer nails associated with systemic lupus erythematosus (SLE) were described in 2005 [13], in 2016 [14] and recently in January, 2017 [15]; but to our knowledge, an isolated finding of pincer nails as the only presenting cutaneous manifestation of SLE has not been reported.…”

Section: Introductionmentioning

confidence: 99%

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Pincer nails: an initial and isolated cutaneous manifestation of systemic lupus erythematosus

Pawar¹

2017

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Introduction. Pincer nail deformity due to systemic lupus erythematosus is a rare phenomenon and only three cases have been reported to date. Objective. To present a case of pincer nails in a systemic lupus erythematosus patient and a brief review of the literature. Case report. A 15-year-old girl presented with multiple painful pincer nail deformities, fever and joint pain of 6 months duration. On evaluation and laboratory investigations the patient fulfilled the criteria for systemic lupus erythematosus. Systemic treatment with glucocorticosteroids and antimalarials led to resolution of fever and joint pain but nail deformities did not improve. Conclusions. Pincer nail may be an early and important sign of systemic lupus erythematosus in certain patients. STRESZCZENIEWprowadzenie. Deformacja w postaci paznokci pincetowatych w przebiegu tocznia rumieniowatego układowego jest zjawiskiem rzadkim. Dotychczas w piśmiennictwie odnotowano zaledwie trzy takie przypadki. Cel pracy. Przedstawienie przypadku paznokci pincetowatych u pacjentki z toczniem rumieniowatym układowym oraz krótki przegląd piśmiennictwa. Opis przypadku. Piętnastoletnia pacjentka zgłosiła się z licznymi bolesnymi zniekształceniami w postaci paznokci pincetowatych, gorączką oraz bólami stawowymi, które utrzymywały się od 6 miesięcy. Badanie przedmiotowe i wyniki badań laboratoryjnych były zgodne z kryteriami diagnostycznymi tocznia rumieniowatego układowego. Po wdrożeniu leczenia ogólnoustrojowego glikokortykosteroidami i lekami przeciwmalarycznymi gorączka i ból stawów ustąpiły, jednak nie uzyskano poprawy stanu paznokci. Wnioski. Paznokcie pincetowate mogą być wczesnym i istotnym objawem tocznia rumieniowatego układowego u niektórych pacjentów.Key words: antimalarials, pincer nails, prednisolone, systemic lupus erythematosus. Słowa kluczowe: leki przeciwmalaryczne, paznokcie pincetowate, prednizolon, toczeń rumieniowaty układowy. INTRODUCTIONPincer nail (also known as omega nail, trumpet nail, convoluted nail, and unguis constringens) is the transverse over-curvature which progressively pinches the nail bed distally [1,2]. It increases in a proximal to distal direction, giving a trumpet appearance. It is more commonly observed on toes than on fingers [2]. It can be hereditary or acquired. An ill-fitting shoe is the most frequent acquired cause [3]. Different dermatoses, such as psoriasis (the most common dermatologic cause), tumors of the nail apparatus and tinea unguium can lead to pincer nail deformity [4,5]. Systemic diseases, placement of arteriovenous fistula (AVF) and use of medications, i.e. β-blockers such as practolol and acebutolol, can lead to pincer nail deformity [6][7][8][9][10][11][12]. Pincer nails associated with systemic lupus erythematosus (SLE) were described in 2005 [13], in 2016 [14] and recently in January, 2017 [15]; but to our knowledge, an isolated finding of pincer nails as the only presenting cutaneous manifestation of SLE has not been reported. CASE REPORTA 15-year-old girl born of non-consanguineous marria...

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Section: Discussionmentioning

confidence: 61%

Section: Discussionunclassified

Section: Case Reportunclassified

Section: Introductionmentioning

confidence: 99%

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Pincer nails: an initial and isolated cutaneous manifestation of systemic lupus erythematosus

Pawar¹

2017

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“…100,106 Many other nail changes have been reported in systemic lupus erythematosus, including Beau's lines, onychomadesis, pitting, chronic paronychia, subungual hyperkeratosis, leukonychia, increased transverse or longitudinal nail curvature, pincer nails, and clubbing. 20,105,107 Onycholysis seems to be the most common finding (25%-40%). 103,104 Red lunula can be the presenting sign of systemic lupus erythematosus 73 and has been found in up to 20% of patients with lupus.…”

Section: Yellow Nail Syndromementioning

confidence: 99%

Nail is Systemic Disorders: Main Signs and Clues

Dehavay

Richert

2021

Dermatologic Clinics

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Nail alterations are common in systemic diseases, but most of them are not specific. Typical nail signs for systemic disease are rare, but should not be missed. Some nail signs should suggest a systemic disease, especially if present on several digits: Beau's lines, onychomadesis, splinter hemorrhages, clubbing, apparent leukonychia, abnormal nail fold capillaries, melanonychia, red lunula and pterygium inversum unguis.

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