Pineal Region Tumors in Childhood

Incidence of pineal tumours. A review of the literature

“…The incidence of pineal tumours is 0.4 to 1% of all intracranial adult tumours [2,3]. Jouvet reported an incidence of 1% [4] (Table 1).…”

“…between 2.7 to 11% [2,3,[8][9][10][11][12]. Raimondi and Tomita [13] reported an incidence of 9.4% corresponding to one of the most elevated incidences in the literature.…”

Tumors of the posterior third ventricular region in pediatric patients: The Indian perspective and a review of literature

“…However, for a majority of primary pineal and GCTs, the MR picture is not diagnostic, and therefore a tissue biopsy becomes mandatory unless the serum markers are pathognomonic. [16] MRI also helps in deciding whether the surgical approach to be used is supra or infratentorial based upon the superior or inferior displacement of the deep venous system by the tumor. The degree of infiltration into the brain stem, the ventricular ependyma or the hypothalamus often helps in predicting the degree of resectability of the lesion.…”

“…[1–7] A proper categorization of these tumors into their histological subtypes considerably helps in effectively managing these lesions as well as in their prognostication. These tumors are rare, comprising less than 11% of all pediatric tumors.…”

“…These tumors are rare, comprising less than 11% of all pediatric tumors. [16] In children, approximately 60% of pineal region tumors are of germ cell origin. [6] A multimodality strategy consisting of surgery (total resection being possible in nearly 30% of tumors), radio- and chemotherapy, often encompassing minimally invasive techniques such as stereotactic biopsy, radiosurgery and endoscopic surgery, has considerably improved outcomes in these lesions.…”