Pinna High Grade Trichoblastic Carcinoma, a Report

Abstract

Trichoblastic carcinoma is a rare malignant hair follicle tumor. It resembles basal cell carcinoma clinically, but different studies emphasize on the importance of differentiating between these two cancers since they have different clinical course which may affect treatment options and follow up. Regardless of its aggressive behavior, no consensus is present for the treatment of trichoblastic carcinoma. We presented the third case of pinna trichoblastic carcinoma, which was surgically excised and followed up for two years post-surgery.

Current Diagnosis and Treatment Options for Cutaneous Adnexal Neoplasms with Follicular Differentiation

“…The cytologic atypia and conspicuous mitotic activity are present in both cells’ phases, which build the tumor. The primary differential diagnosis of a trichoblastic carcinosarcoma is sarcomatoid basal cell carcinoma (basal cell carcinosarcoma), which is diagnosed primarily in 94% of cases [ 48 ]. The epithelial component stains positive for keratins on the microscopic image, including CKAE1/3 (cytokeratin AE1/3) and CK5/6 (cytokeratin 5/6), and p63.…”