Piperidine alkaloid content of Picea (spruce) and Pinus (pine)

Stermitz, Frank R.; Tawara, Jeanne N.; Boeckl, Maximiliane; Pomeroy, Marc; Foderaro, Tommaso A.; Todd, Fred G.

doi:10.1016/s0031-9422(00)90645-9

Cited by 47 publications

(22 citation statements)

References 14 publications

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“…These results are in consistent with the findings of other researchers, who have reported a high degree of qualitative and quantitative variability of piperidine alkaloids among tissues within species. 19,20 The abundance and diversity of alkaloids in aerial parts of the plant may be attributed to the protective mechanism of the plant against animals and pathogens. 21 Prosopine and prosopinine alkaloids, had been reported in P. africana, 22 however, the analysis conducted by DART-MS confirmed the presence of these alkaloids in P. juliflora.…”

Section: Resultsmentioning

confidence: 99%

Study of the distribution profile of piperidine alkaloids in various parts of Prosopis juliflora by the application of Direct Analysis in Real Time Mass Spectrometry (DART-MS)

Singh

Verma

2012

Nat. Prod. Bioprospect.

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Direct Analysis in Real Time Mass Spectrometry (DART-MS) was applied to identify and study the distribution profile of piperidine alkaloids in different parts of Prosopis juliflora, without isolation and separation of the compounds by standard chromatographic techniques. With the help of DART-MS, chemical fingerprint of raw plant parts were generated, which revealed the presence of piperidine alkaloids in leaf, pod and flower. A comparative study of the distribution pattern, showed variation in the presence and distribution of these alkaloids in various parts of P. juliflora. The leaves and pod displayed the largest alkaloid pattern with a total of 12 different alkaloids in each part, whereas only 4 alkaloids were present in flower. Alkaloids: julifloridine, prosopine, prosopinine and prosafrinine were ubiquitously distributed in all the alkaloid rich plant parts. Juliprosopine was pre-eminet alkaloid in leaf, whereas pod and flower displayed copious amounts of julifloridine.

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Section: Resultsmentioning

confidence: 99%

Study of the distribution profile of piperidine alkaloids in various parts of Prosopis juliflora by the application of Direct Analysis in Real Time Mass Spectrometry (DART-MS)

Singh

Verma

2012

Nat. Prod. Bioprospect.

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“…pallasiana cones showed potent anthelmintic activity as shown in Tables 3 and 4. Several groups of natural compounds mainly flavonoids (Niemann, 1988), tannins (Harborne and Baxter, 2001) and piperidine alkaloids (Stermitz et al, 1994) have been recognized in some Pinus species. Tannins are applied as astringents, anti-hemorrhagics and anti-abortives in veterinary medicine.…”

Section: Resultsmentioning

confidence: 99%

Evaluation of some plants used in Turkish folk medicine against parasitic infections for their in vivo anthelmintic activity

Kozan

Küpeli

Yeşilada

2006

Journal of Ethnopharmacology

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“…(Chinese name Zhe Beimu) being the first one from genus Fritillaria [4]. Alkaloids, as the main active ingredients, contribute to the antitussive and expectorant function and they are usually extracted by classical solvent extraction [5,6]. According to Chinese Pharmacopeia (2010 edition), the content of peimine and peiminine in the bulb of F. Thunbergii extracted by the CHCl 3 /CH 3 OH = 4:1 and analyzed by HPLC must be higher than 0.1% for medical use (chemical structure of peimisine, peimine, and peiminine see Figure 1) [7].…”

Section: Introductionmentioning

confidence: 99%

Optimization of Supercritical Fluid Extraction of Total Alkaloids, Peimisine, Peimine and Peiminine from the Bulb of Fritillaria thunbergii Miq, and Evaluation of Antioxidant Activities of the Extracts

et al. 2016

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Supercritical fluid extraction (SFE) was used to extract total alkaloids, peimisine, peimine and peiminine from the bulb of Fritillaria thunbergii Miq. The antioxidant capacity of the extracts was evaluated by DPPH radical scavenging activity (DPPH-RSA), ABTS radical scavenging activity (ABTS-RSA) and ferric reducing capacity (FRAP) assay. A central composite design (CCD) with four variables and five levels was employed for optimization of process parameters, and response surface plots were constructed in accordance with a second order polynomial model. Under optimal conditions of 3.0 h, 60.4 °C, 26.5 MPa and 89.3% ethanol, the highest yields were predicted to be 3.8 mg/g for total alkaloids, 0.5 mg/g for peimisine, 1.3 mg/g for peimine and 1.3 mg/g for peiminine, and the antioxidant capacity of extracts displayed EC50, DPPH value of 5.5 mg/mL, EC50, ABTS value of 0.3 mg/mL and FRAP value of 118.2 mg ascorbic acid equivalent (AAE)/100 g.

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Piperidine alkaloid content of Picea (spruce) and Pinus (pine)

Cited by 47 publications

References 14 publications

Study of the distribution profile of piperidine alkaloids in various parts of Prosopis juliflora by the application of Direct Analysis in Real Time Mass Spectrometry (DART-MS)

Study of the distribution profile of piperidine alkaloids in various parts of Prosopis juliflora by the application of Direct Analysis in Real Time Mass Spectrometry (DART-MS)

Evaluation of some plants used in Turkish folk medicine against parasitic infections for their in vivo anthelmintic activity

Optimization of Supercritical Fluid Extraction of Total Alkaloids, Peimisine, Peimine and Peiminine from the Bulb of Fritillaria thunbergii Miq, and Evaluation of Antioxidant Activities of the Extracts

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