2023
DOI: 10.3389/fbioe.2023.1166334
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Piranha solution treatment: A facile method for improving the antithrombotic ability and regulating smooth muscle cell growth on blood contact materials

Abstract: Blood contact materials require strong anti-fouling capabilities to avoid thrombus formation. Recently, TiO2-based photocatalytic antithrombotic treatment has gained focus. Nevertheless, this method is restricted to titanium materials with photocatalytic abilities. This study offers an alternative solution that can be applied to a broader range of materials: piranha solution treatment. Our findings revealed that the free radicals generated by the treatment effectively altered the surface physicochemical proper… Show more

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Cited by 4 publications
(2 citation statements)
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“…On the other hand, Piranha solution-treated PEEK samples showed a higher wettability compared with sulfuric acid-treated samples. This can be the result of the increased number of functional groups on the surface caused by the Piranha solution, as stated in multiple references [ 17 , 18 , 26 ]. The present report evaluated roughness and wettability.…”
Section: Discussionmentioning
confidence: 99%
“…On the other hand, Piranha solution-treated PEEK samples showed a higher wettability compared with sulfuric acid-treated samples. This can be the result of the increased number of functional groups on the surface caused by the Piranha solution, as stated in multiple references [ 17 , 18 , 26 ]. The present report evaluated roughness and wettability.…”
Section: Discussionmentioning
confidence: 99%
“…Surface wettability, a typical material property that occurs commonly in nature, is gaining increasing attention for both scientific researches and biomedical applications in antifouling materials ( Xie et al, 2019 ; He et al, 2021a ; He et al, 2021b ; Chang et al, 2022 ; Eloffy et al, 2022 ; Rasitha et al, 2022 ; Seli et al, 2022 ; Selim et al, 2022 ; He et al, 2023a ; He et al, 2023b ; He et al, 2023c ), blood contacting materials ( Yang et al, 2020 ; Li et al, 2021 ; Li et al, 2022a ; Li et al, 2022b ), etc. ( Wu et al, 2018 ; Li et al, 2020a ; Wang et al, 2020 ; Guo et al, 2021 ; Han and Gong, 2021 ; Saji, 2021 ; Zhang et al, 2021 ; Zhu et al, 2021 ; Al-Bishari et al, 2022 ; Wang et al, 2022a ; Luo et al, 2022 ; Yao et al, 2022 ; Yu et al, 2022 ; Zhang et al, 2022 ; Gresham and Neto, 2023 ; Li et al, 2023 ; Liao et al, 2023 ; Pan et al, 2023 ). Surfaces can be categorized according to the water contact angle (WCA), as hydrophilic (for WCA <90°) or hydrophobic (for WCA >90°) ( Li et al, 2020b ; Yang et al, 2022 ; Zhao et al, 2022 ).…”
Section: Introductionmentioning
confidence: 99%