Pitfalls and Limitations of Radionuclide Planar and Hybrid Bone Imaging

Agrawal, Kanhaiyalal; Marafi, Fahad; Gnanasegaran, Gopinath; Wall, Hans Van der; Fogelman, Ignac

doi:10.1053/j.semnuclmed.2015.02.002

Cited by 47 publications

(31 citation statements)

References 72 publications

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“…The sensitivity of the bone scan for lytic lesions depends on the magnitude of the osteoblastic reaction. Pitfalls include post chemotherapy lytic lesions (particularly in breast and lung cancer), bone infarcts and mucinous cystic lesions [51]. Relatively low osteoblastic activity and high osteoclastic activity limit the detection of lesions on bone scans [52].…”

Section: Tc99m Bone Scanmentioning

confidence: 99%

State-of-the-art imaging for diagnosis of metastatic bone disease

Isaac

Dalili

et al. 2020

Radiologe

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Table 1 Epidemiological indicators: total number of cancer cases in Germany in 2013 (modified according to [21]) New cases Women Men Death Women Men Absolute number 229,920 252,550 Absolute number 101,779 121,314 Mean age at diagnosis 67.2 68.3 Mean age at diagnosis 74.3 73.3 Raw rate 558.4 639.9 Raw rate 247.2 307.7 Age-standardized rate a 351.2 434.1 Age-standardized rate a 126.7 196.5 Current trend +0.8%-0.5% Current trend-0.7%-1.2% Age-standardized rate a 327.9 447.6 Age-standardized rate a 126.8 211.8 Prognosis for 2020 (absolute number) 244,100 274,900 Prognosis for 2020 (absolute number)-0.8%-1.5%

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Section: Tc99m Bone Scanmentioning

confidence: 99%

State-of-the-art imaging for diagnosis of metastatic bone disease

Isaac

Dalili

et al. 2020

Radiologe

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“…Technetium-99m methylene diphosphonate ( 99m Tc-MDP) bone scintigraphy is one of the most commonly performed nuclear medicine studies. It is highly sensitive in detection of different benign and malignant bone pathologies[ 13 ]. The skeleton is made up of inorganic calcium hydroxyapatite crystals.…”

Section: Nuclear Medicine Imaging In Onmentioning

confidence: 99%

“…Hybrid SPECT/CT provides both anatomical and metabolic information (Figures 2 and 3 )[ 13 ]. CT component is helpful in localization and characterization of increased osteoblastic activity seen on planar or SPECT only images.…”

Section: Nuclear Medicine Imaging In Onmentioning

confidence: 99%

“…With wider use of PET/CT and reintroduction of the 18 F-fluoride bone scan, its role in ON has been evaluated by researchers. 18 F-fluoride is a positron-emitting radiotracer[ 13 ]. After diffusion through capillaries into bone extracellular fluid, 18 F-ions exchange with hydroxyl groups in hydroxyapatite crystals to form fluorapatite[ 13 ].…”

Section: Nuclear Medicine Imaging In Onmentioning

confidence: 99%

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Nuclear medicine imaging in osteonecrosis of hip: Old and current concepts

Agrawal

Trıpathy

Sen

et al. 2017

WJO

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Osteonecrosis (ON) is caused by inadequate blood supply leading to bone death, which results in the collapse of the architectural bony structure. Femoral head is the most common site involved in ON. Magnetic resonance imaging (MRI) is a commonly used imaging modality to detect early ON. When MRI is inconclusive, bone scan is helpful in detecting ON during early phase of the disease. As newer nuclear medicine equipment, like single photon emission computed tomography/computed tomography (CT) and positron emission tomography/CT, are emerging in medical science, we review the role of these imaging modalities in ON of femoral head.

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“…Hemen ardından ortalama 2-3 dakika süren ikinci faz olan kan havuzu fazı görüntüleri alınır. Ortalama üç saat sonra üçüncü faz olan kemik fazı görüntülemesi yapılır [10][11] . Stres fraktürü tanısında ilk olarak direkt grafi istenilmektedir ancak direkt grafi erken döenmde negatif olabilmektedir.…”

Section: Tanıda Kullanılan Nükleer Tıp Görüntüleme Yöntemleri 1 üç Funclassified

Stres Fraktürüne Nükleer Tıp Yaklaşımı

Salmanoglu¹,

Pazarci²

2017

Arşiv Kaynak Tarama Dergisi

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Stress fracture is a common sports injury. It is result of recurrent strain to normal bone, generally. The diagnosis of stress fracture is important in terms of patient management.Three phase bone scintigraphy is a very sensitive method in the diagnosis of the stress fracture. Bone SPECT, SPECT/CT, PET/CT, PET/MR imaging modalities are other radionuclide imaging techniques which are helpful in the diagnosis of stress fracture. We aimed to describe the approach of the nuclear medicine in the diagnosis of stress fracture in this article. ÖZStres fraktürü, sık görülen bir spor yaralanmasıdır. Genellikle normal kemiğe tekrarlayan zorlamalar sonucu ortaya çıkmaktadır. Stres fraktürünün tanısını koymak hasta yönetimi açısından önemlidir. Üç fazlı kemik sintigrafisi stres fraktürü tanısını koymada çok duyarlı bir yöntemdir. Kemik SPECT, SPECT/BT, PET/BT, PET/MR görüntüleme yöntemleri stres fraktürü tanısını koymada yardımcı diğer radyonüklid görüntüleme yöntemleridir. Biz bu yazıda stres fraktürü tanısında nükleer tıp yaklaşımını anlatmayı amaçladık. Anahtar kelimeler: Stres fraktürü, üç fazlı kemik sintigrafisi, radyonüklid görüntüleme. GirişBaşta Ortopedi ve Travmatoloji hekimleri olmak üzere klinisyenlerin sık karşılaştığı kas-iskelet sistemi patolojilerinden birisi stres fraktürüdür. Stres fraktürü, tekrarlayan mikrotravma

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Pitfalls and Limitations of Radionuclide Planar and Hybrid Bone Imaging

Cited by 47 publications

References 72 publications

State-of-the-art imaging for diagnosis of metastatic bone disease

State-of-the-art imaging for diagnosis of metastatic bone disease

Nuclear medicine imaging in osteonecrosis of hip: Old and current concepts

Stres Fraktürüne Nükleer Tıp Yaklaşımı

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