2024
DOI: 10.1177/09760016241239858
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Pitfalls in the Interpretation of Biomarkers in Neonatal Sepsis

Rajasri Ambalam Ganesamoorthi,
Poongodi Santhana Kumarasamy

Abstract: Background: In India, 25%–65% of neonatal deaths are due to sepsis. Since it produces nonspecific symptoms, it is difficult to diagnose and manage. The present study assessed the value of brain natriuretic peptide (BNP) and C-reactive protein (CRP) to predict sepsis along with blood culture. Materials and Methods: Samples were collected from 90 neonates with suspected sepsis, submitted for blood culture, CRP by latex agglutination kit, and BNP by ELISA. Results: Of the 90 cases, blood culture was positive in 2… Show more

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