1953
DOI: 10.1001/archneurpsyc.1953.02320350050005
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Pituitary-Adrenal Cortex Reactivity in Schizophrenic Patients

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Cited by 4 publications
(2 citation statements)
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“…Numerous workers have attempted to explain the beneficial effects of ICT and E C T through activity of the hypothalamic-anterior pitui-tary-adrenal cortex axis, some of these concepts regarding I C T and ECT as non-specific stressors within the framework of the General Adaptation Syndrome (GAS) of Selye (45,47,98,104,149,308,425,445, ++6). 'The elevation of plasma 17-hydroxycorticosteroid level when the peripheral seizure is blocked by dilantiii and SKFz599 indicates direct central stimulation as the source (48); since the anterior pituitary does not respond directly to electrical stimulation, the hypothalamo-anterior pituitary system is implicated, with release of ACTH.…”
Section: Some Theories Of Mode Of Action Of Shock Therapiesmentioning
confidence: 99%
“…Numerous workers have attempted to explain the beneficial effects of ICT and E C T through activity of the hypothalamic-anterior pitui-tary-adrenal cortex axis, some of these concepts regarding I C T and ECT as non-specific stressors within the framework of the General Adaptation Syndrome (GAS) of Selye (45,47,98,104,149,308,425,445, ++6). 'The elevation of plasma 17-hydroxycorticosteroid level when the peripheral seizure is blocked by dilantiii and SKFz599 indicates direct central stimulation as the source (48); since the anterior pituitary does not respond directly to electrical stimulation, the hypothalamo-anterior pituitary system is implicated, with release of ACTH.…”
Section: Some Theories Of Mode Of Action Of Shock Therapiesmentioning
confidence: 99%
“…Fry (95), using the epinephrine test on eosinophils, concluded that the pituitary adrenocortical system was not impaired in schizophrenia. Hobbs, Goddard, and Stevenson (139), investigating the diurnal cycle of blood eosinophils and body temper'iturc, found no differencc between chronic schizophrenic patients and normal controls.…”
Section: A D R E N a L C O R T E X I N S C R I Z O P H R E N I Amentioning
confidence: 99%