Pituitary Apoplexy

Reid, Robert L.

doi:10.1001/archneur.1985.04060070106028

Cited by 158 publications

(82 citation statements)

References 52 publications

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“…Pituitary apoplexy usually occurs spontaneously since the blood supply to a tumor is precarious, but it has been described in association with a great variety of events, including minor head trauma [3], medications [1], and dynamic pituitary function test [9,10], although the mechanism leading to apoplexy is obscure in most of these events. This patient presumably had massive bleeding from an acute gastric ulcer.…”

Section: Introductionmentioning

confidence: 99%

Amelioration of Acromegaly after Pituitary Infarction Due to Gastrointestinal Hemorrhage from Gastric Ulcer.

et al. 1999

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Section: Introductionmentioning

confidence: 99%

Amelioration of Acromegaly after Pituitary Infarction Due to Gastrointestinal Hemorrhage from Gastric Ulcer.

et al. 1999

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“…She had experienced the abrupt onset of severe headache associated with nausea and blurring vision with diplopia. The visual disturbance and headache gradually improved but 3 mmol/l), hypernatraemia (143-151 mmol/l) and low specific gravity of urine. Test for C-reactive protein was negative and the erythrocyte sedimentation rate was 12 mm/h.…”

Section: Case Reportmentioning

confidence: 98%

Simultaneous occurrence of transient resolving thyrotoxicosis due to painless thyroiditis, hypopituitarism and diabetes insipidus following pituitary apoplexy

Sasaki

OHNISHI

Okudera

et al. 1991

Postgraduate Medical Journal

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“…3,9,24,26,29,30 Pituitary apoplexy is usually heralded by an abrupt onset of severe headache, nausea, vomiting, deterioration of vision, restriction of visual fields, ophthalmoplegia, or, infrequently, altered sensorium. The unique clinical manifestation was first described by Bleibtreu in 1905, 5 while the term currently ascribed to the condition (pituitary apoplexy) was first coined in 1950 by Brougham et al, 8 who described 5 patients who died suddenly, in whom postmortem autopsy revealed hemorrhage and necrosis of a pituitary adenoma.…”

Section: Pituitary Apoplexymentioning

confidence: 99%

“…Multiple endocrine deficiencies manifesting as weakness, lethargy, depressed mental status, nausea, and vomiting secondary to the destruction of the gland may occur less frequently because of the great functional reserve of the pituitary gland, which can function with as little as 10% of viable tissue. 6,20,24,26 …”

Section: Pituitary Apoplexymentioning

confidence: 99%

Combined chronic lymphocytic leukemia and prolactinoma: a rare occurrence in a patient presenting with pituitary apoplexy

Krisht

Palmer

Couldwell

2013

JNS

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Pituitary involvement in B-cell CLL and pituitary apoplexy, independently, are 2 rare events. Their co-occurrence in addition to the presence of prolactin-secreting adenoma cells, however, has never been described in the literature. We present the case of a combined pituitary CLL and prolactinoma apoplexy in a 77-year-old man to highlight the importance of imaging the brain in patients with CLL who present with signs and symptoms of pituitary apoplexy. To the best of our knowledge, there are only 2 other reported cases of CLL manifesting as a pituitary mass lesion.11,21 The current case is the first instance of a combined pituitary CLL-prolactinoma presenting with pituitary apoplexy. This case illustrates the need to carefully evaluate pituitary tumor specimens from patients with CLL for small lymphocytic infiltration, notwithstanding the presence of pituitary adenoma cells. Case ReportHistory and Examination. This 77-year-old man with untreated CLL diagnosed 8 years earlier presented with a 2-day history of severe bifrontal headaches associated with nausea and vomiting, including left facial numbness and complete ophthalmoplegia of his left eye. Three weeks prior to his admission he was hospitalized at an outside hospital for a pulmonary embolus and discharged on a regimen of 5 mg of oral warfarin at bedtime along with subcutaneous injections of 115 mg of enoxaparin every 12 hours as a bridging therapy. At his initial examination at our institution, he was awake, alert, and fully oriented. Positive findings included complete dense ophthalmoplegia of the left eye, diminished facial sensation to all sensory modalities along the V1 and V2 distributions, and right eye blindness secondary to glaucoma. Visual acuity remained Combined chronic lymphocytic leukemia and prolactinoma: a rare occurrence in a patient presenting with pituitary apoplexy The authors describe a rare case of combined pituitary chronic lymphocytic leukemia (CLL) and prolactinoma in a 77-year-old man presenting with apoplexy. This case highlights the importance of evaluating the pituitary gland in patients with CLL who present with clinical manifestations of apoplexy as well as the need to carefully evaluate pathological specimens from the gland for the presence of lymphocytic cells in those patients. This is the first reported case of a combined CLL-prolactinoma pituitary lesion presenting with apoplexy.

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Pituitary Apoplexy

Cited by 158 publications

References 52 publications

Amelioration of Acromegaly after Pituitary Infarction Due to Gastrointestinal Hemorrhage from Gastric Ulcer.

Amelioration of Acromegaly after Pituitary Infarction Due to Gastrointestinal Hemorrhage from Gastric Ulcer.

Simultaneous occurrence of transient resolving thyrotoxicosis due to painless thyroiditis, hypopituitarism and diabetes insipidus following pituitary apoplexy

Combined chronic lymphocytic leukemia and prolactinoma: a rare occurrence in a patient presenting with pituitary apoplexy

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