Abstract:4073
Poster Board III-1008
Introduction
Despite continuing advances in iron chelation therapy, endocrine dysfunction is common in chronically transfused patients with iron overload. In thalassemia major, hypogonadotropic hypogonadism (HH), impaired glucose tolerance, delayed growth, and hypothyroidism are common, but gonadotrophic function is the most vulnerable and least reversible. Unfortunately, clinical effects of gonadotrophe iron toxicity… Show more
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