BACKGROUNDTrichoscopy is becoming increasingly popular in diagnosing hair and scalp
diseases. Scalp involvement in pemphigus is common. The scalp may be the first or
only site of clinical manifestation of the disease.OBJECTIVEThe aim of this study was to analyze whether trichoscopy may be useful in aiding
differential diagnosis of scalp lesions in patients with pemphigus vulgaris and
pemphigus foliaceus.METHODSTrichoscopy was performed in 19 patients with scalp lesions in the course of
pemphigus (9 patients with pemphigus vulgaris and 10 with pemphigus foliaceus). In
all patients, the diagnosis of scalp pemphigus was confirmed by histopathology.
The working magnification was 20-fold and 70-fold.RESULTSThe most frequently observed trichoscopy features of pemphigus lesions were:
extravasations (18/19; 94.7%) and yellow hemorrhagic crusts (11/19; 57.9%). Yellow
dots with whitish halo were observed in 6/19 (31.6%) patients with pemphigus.
White polygonal structures were observed in pemphigus foliaceus (6/10; 60%), but
not in pemphigus vulgaris. Vascular abnormalities were more frequent in pemphigus
vulgaris, when compared to pemphigus foliaceus, and were associated with a severe
course of disease. Linear serpentine vessels were the most frequent vascular
abnormality in patients with pemphigus vulgaris and pemphigus foliaceus (77.8% and
30%, respectively).CONCLUSIONTrichoscopy may serve as a useful supplementary method in the differential
diagnosis of pemphigus, especially in cases of desquamative or exudative lesions
limited to the scalp. Extravasations, yellow hemorrhagic crusts, yellow dots with
whitish halo, white polygonal structures and linear serpentine vessels are
trichoscopy features which may suggest the diagnosis of pemphigus.