Pityriasis rubra pilaris – a retrospective single center analysis over eight years

Abstract

PRP type I is a severe, chronic inflammatory dermatosis responding hesitantly to classic systemic therapies. Tumor necrosis factor-alpha antagonists are an effective treatment option for difficult cases.

Pityriasis rubra pilaris: clinicopathological study of 32 cases from Lebanon

“…Successful treatment of PRP can be challenging . To date, oral retinoids (acitretin or isotretinoin) are considered to be the most effective therapeutic modality in classic forms of PRP.…”

British Association of Dermatologists and British Photodermatology Group guidelines for the safe and effective use of psoralen–ultraviolet A therapy 2015

“…For some indications PUVA is the first‐line phototherapy (favoured over NB‐UVB). These indications include MF beyond patch stage, pustular psoriasis, pompholyx, hand and foot eczema and, probably, adult generalized pityriasis rubra pilaris …”

“…Many patients prefer oral PUVA as it involves less time in the hospital unit, but some choose topical PUVA, in particular to avoid the inconvenience of eye protection. 9.0 Psoralen-ultraviolet A for specific dermatoses 9.1 Psoriasis 9.1.1 Is oral psoralen-ultraviolet A therapy more effective than topical psoralen-ultraviolet A therapy in patients with chronic plaque psoriasis?…”

Pityriasis rubra pilaris-like eruption following insulin therapy initiation

“…Although possible, a fortuitous association “insulin therapy—idiopathic PRP” seems unlikely in our case because of the rapid resolution of the rash, as opposed to the classical chronic course of idiopathic PRP, even with the use of systemic treatments, such as retinoids [1]. …”

“…Pityriasis rubra pilaris (PRP) is a chronic disorder of keratinization of unclear pathogenesis [1]. It typically manifests as erythematous and scaly cutaneous plaques with islands of spared skin associated with follicular scaly papules and orange palmar and plantar keratoderma.…”