Pivotal role of boron supplementation on bone health: A narrative review

Rondanelli, Mariangela; Faliva, Milena Anna; Peroni, Gabriella; Infantino, Vittoria; Gasparri, Clara; Iannello, Giancarlo; Perna, Simone; Riva, Antonella; Petrangolini, Giovanna; Tartara, Alice

doi:10.1016/j.jtemb.2020.126577

Cited by 47 publications

(25 citation statements)

References 41 publications

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“…While boron has not definitively been established as an essential mineral for humans, there is increasing evidence from in vitro, animal, and human studies demonstrating the beneficial health effects of boron (Białek et al 2019;Nielsen and Eckhert 2020;Rondanelli et al 2020). In addition, boron deficiencies in animals have been associated with adverse effects (EFSA NDA Panel 2004).…”

Section: The Role Of Boron In Nutrition Of Plants and Animalsmentioning

confidence: 99%

“…In humans, large amounts of boron are well-tolerated and dietary levels of boron have been shown to have a role in mineral metabolism, influencing the metabolism and utilisation of other essential elements such as calcium (Hunt et al 1997;Nielsen and Penland 1999). In addition, there is evidence that boron has beneficial effects on bone calcification and maintenance, and boron deficiency has consistently been shown to cause a reduction in blood indices such as steroid hormone concentrations (Naghii and Samman 1993;EFSA NDA Panel 2004;Rondanelli et al 2020).…”

Section: The Role Of Boron In Nutrition Of Plants and Animalsmentioning

confidence: 99%

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Assessment of consumer exposure to boron in cleaning products: a case study of Canada

DeLeo

Stuard

Kinsky

et al. 2021

Critical Reviews in Toxicology

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Boron is an essential mineral for plants, and as such, is a normal dietary constituent for humans. Humans may be naturally exposed to boron through food and drinking water, or via anthropogenic sources such as consumer products. The World Health Organisation established an acceptable safe range of population mean intakes for boron of 1-13 mg/day. Most studies of dietary boron intake show a range of 1-2 mg/day. Consumer products have been estimated to contribute a geometric mean daily intake of 0.1 mg to total boron exposure; however, there are few published surveys of consumer exposure to boron from use of cleaning products. The Government of Canada published a draft screening assessment report of boric acid, its salts and precursors that included estimates of consumer exposure to boron found as ingredients in consumer products. The manufacturers of consumer cleaning products conducted a survey of boron content of current products and estimated exposure using the publicly available exposure tool ConsExpo Web. Dermal exposures to boron during cleaning product use were estimated to result in annual internal exposures ranging from (0.001 to 0.36 lg/kg bw/ day based on dermal absorption of 0.5%. Using a conservative point of departure for hazard assessment (2,900 lg boron/kg bw/day), estimated margins of exposure for dermal exposures to boron from cleaning product use range from 8,056 to >1,000,000. This work demonstrates that exposure to boron from cleaning product use is very low and essentially insignificant when compared to other (e.g. dietary) sources of boron intake by Canadian consumers.

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Section: The Role Of Boron In Nutrition Of Plants and Animalsmentioning

confidence: 99%

Section: The Role Of Boron In Nutrition Of Plants and Animalsmentioning

confidence: 99%

Assessment of consumer exposure to boron in cleaning products: a case study of Canada

DeLeo

Stuard

Kinsky

et al. 2021

Critical Reviews in Toxicology

View full text Add to dashboard Cite

show abstract

“…The element boron is essential for all plant and animal life [1][2][3][4]. The interaction of calcium (Ca) and boron (B) has been observed in plants, bacteria, animals, and humans, and has been documented in several papers [1][2][3][4][5][6][7]. However, the specific nature of the Ca/B interaction is still under experimental investigation.…”

Section: Introductionmentioning

confidence: 99%

“…The characterization of this complex has been reported previously. The biological and biochemical action of calcium fructose in borate structure has been studied and found that it has a chemical structure similar to that of natural boro-carbohydrates found in edible plants [4][5][6][7][8]. The chemical status of boron in nutrition is very important.…”

Section: Introductionmentioning

confidence: 99%

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Characterization Studies on Calcium Borate Compound Modified by ZnCO3, CaCO3 and Fructose

El-Damrawi¹,

Abdelghany²,

Saad³

2021

J. Basic Appl. Sci.

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Calcium fructoborate solid materials of formula Ca(C6H10O6BO)2 ·3.5H2O were prepared by chemical wet technique. The neutral trigonal form of boron organic ester with fructose, under the solid form, is prepared and modified in solution in the anionic tetrahedral form; the borate compound is investigated by XRD spectroscopy. An ideal strong amorphous forming material is obtained upon modification with ZnCO3 or CaCO3. 11B NMR solids and solution and Raman spectroscopy were developed to determine different types and the amount of borate derivative present in products. The modifier portion from calcium carbonate and fructose are consumed for boron transformation from three to four coordinated units. Raman spectra of pure B2O3 confirm the presence of the borate boroxol ring as the main structural units. But different borate units are formed upon modification by calcium carbonate and fructose. Modification by ZnCO3 had a few effects on boron transformation. The chemical shift of 11 B NMR spectra is remaining unchanged upon its addition.

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Probabilistic health risk assessment for residents exposed to potentially toxic elements near typical mining areas in China

Hao

Lv³

et al. 2022

Environ Sci Pollut Res

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Pivotal role of boron supplementation on bone health: A narrative review

Cited by 47 publications

References 41 publications

Assessment of consumer exposure to boron in cleaning products: a case study of Canada

Assessment of consumer exposure to boron in cleaning products: a case study of Canada

Characterization Studies on Calcium Borate Compound Modified by ZnCO3, CaCO3 and Fructose

Probabilistic health risk assessment for residents exposed to potentially toxic elements near typical mining areas in China

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