2024
DOI: 10.1002/cam4.6917
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Pivotal role of myeloid‐derived suppressor cells in infection‐related tumor growth

Nozomi Ito,
Hironori Tsujimoto,
Hiromi Miyazaki
et al.

Abstract: BackgroundIn this study, we investigated infection‐related tumor growth, focusing on myeloid‐derived suppressor cells (MDSCs) in clinical and experimental settings.Patients and MethodsIn the clinical study, a total 109 patients who underwent gastrectomy or esophagectomy were included. Blood samples were collected from a preoperative time point through 3 months after surgery, and MDSCs were analyzed using flow cytometry. In animal experiments, peritonitis model mice were created by CLP method. We investigated t… Show more

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