Place des bactériémies à Staphylococcus aureus au CHU de Fann à Dakar

Seydi, Moussa; Sow, A. I.; Soumare, M.; Diallo, Hamidou; Hatim, B; Tine, Roger; Diop, Bernard Marcel; Sow, Papa Salif

doi:10.1016/j.medmal.2004.03.003

Cited by 12 publications

(5 citation statements)

References 19 publications

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“…High resistance (64%) of S. aureus infection was observed in Asian countries [5], while in north America, the rate varies from 36% to 62.6% [6][7][8]. In European countries resistance range from 20 to 50% [9][10][11]. Result from nine (9) African countries reported by their National data Institute showed high level of resistance between 12% to 80% with few countries exceeding 82% [12][13][14].…”

Section: Resistantmentioning

confidence: 99%

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Antibiotic Resistance Pattern of Staphylococcus aureus and Associated Risk Factors in the Adamaoua and Far North Regions of Cameroon

Mohamadou

Essama

Akwah

et al. 2020

MRJI

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Background: Infections due to Staphylococcus aureus (S. aureus) have been recognized as an important public health problem worldwide. Resistant S. aureus strains emerged and its prevalence has been on the rise. Many risk factors were identified as comorbidities and impact seriously the health state of infected individual by resistant Staphylococcus aureus. We focus our study on two of these risk factors (HIV-infection and diabetes) which may constitute high potential health conditions for emergence of resistant S. aureus strains. Methods: A Cross sectional study was conducted during 19 months in five laboratories in the northern Cameroon. Collection of clinical samples from nine different types of specimens and first identifications were conducted in the various sites of study. Selected strains were transported in Yaoundé using standard procedure. Identification and drug susceptibility testing was performed using the disk diffusion method. Questionnaires were submitted to all the participants after an approved written and oral consent. HIV and Glycemia test were carried out on each patient in case their status was not known. During the study, 380 strains of Staphylococcus aureus were identified. Antimicrobial test was achieved using 16 different antibiotics. Results: Result showed that 202/380 (53.2 %) of Staphylococcus aureus were resistant to at least three antibiotics (multiresistant) from three different families. Multiresistant strains displayed high resistance to cotrimoxal (76.7 %) followed by penicillin (66.8 %), tetracyclin (57.4 %) and oxacillin (51.5%). While high rate of sensitivity were obtained for rifampicin (78.7 %), fusidic acid (65.8 %), lincomycin (60.5 %) and minocyclin (58.9 %). Few participants 8.9 % were tested HIV positive and 7.9% were living with diabetes. Strains isolated from participants living with these diseases presented higher rate of resistance to antibiotics. Conclusion: The rate of multiresistant Staphylococcus aureus are constantly in progress in northern Cameroon, most of the strains originated from community. These strains exhibited high resistance level to cotrimoxazol while displaying high sensitivity to rifampicine. People living with chronic diseases presented high resistance to antibiotic recommended for S. aureus infection treatment.

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Section: Resistantmentioning

confidence: 99%

“…Mansour et al; MRJI, 30(11):[1][2][3][4][5][6][7][8][9][10][11] 2020; Article no.MRJI. Eleven of the twenty nine women 37.9 % were pregnant.…”

mentioning

confidence: 99%

Antibiotic Resistance Pattern of Staphylococcus aureus and Associated Risk Factors in the Adamaoua and Far North Regions of Cameroon

Mohamadou

Essama

Akwah

et al. 2020

MRJI

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“…In North America the rates varied according to studies from 36 to 62.6% [9][10][11]. The same variability is observed in south European countries, where the oxacillin resistance rate ranged from 20 to 50% [11][12][13][14][15]. The result of 9 African countries reported by their National data Institute showed a high prevalence rate, between 12% to 80%, with some countries exceeding 82% [16][17].…”

Section: Introductionmentioning

confidence: 86%

Methicillin-Resistant Staphylococcus aureus (MRSA): A major concern in the Northern Cameroon

Gaké¹,

Bamia²,

Mohamadou³

et al. 2022

GSC Biol. Pharm. Sci.

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Staphylococcus aureus remains the most virulent pathogenic staphylococcal species known to human beings. Oxacillin is still the best antibiotic used for treating infections with S. aureus. However, cases of resistance are increasingly recorded and cause a serious public health concern. The objective of this study was to evaluate the resistance of S. aureus to oxacillin. The study was carried out in the North region of Cameroon on strains isolated at Centre Pasteur in Cameroon. Three hundred (300) strains of Staphylococcus were recorded, among them 200 (66.67%) were identified as Staphylococcus aureus, mainly coming from six (06) different types of samples. The susceptibility test to oxacillin was carried out using two methods: the diffusion method using discs (oxacillin, cefoxitin) and the determination of Minimum Inhibition Concentration (MIC) by E-test. Overall 84 (42%) resistant strains were detected by both methods. Cervico-vaginal specimen harbored the highest number of S. aureus strains (41%), compared to other specimen types. However, pus recorded the highest number of resistant cases (79%), followed by semen culture (50%). Among all resistant strains recorded, 84.5% were tested positive for beta-lactamase production.

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“…These bacteria are known to provoke boils, whitlow, abscesses, conjunctivitis, ear infection, endometriosis, salpingitis, pneumonia, meningitis, osteomyelitis, acute cystitis and food poisoning. A high rate (72%) of MRSA bacteremia, in particular among nosocomial bacteremia, was found in Dakar (Senegal) [3]. In West Africa, the treatment of these infections is a frequent problem due to the high prevalence of MDR bacteria [2].…”

Section: Staphylococcimentioning

confidence: 99%

“…During the last decade, the prevalence of MDR bacteria has increased despite the measures of control [1][2][3][4]. During the last decade, the prevalence of MDR bacteria has increased despite the measures of control [1][2][3][4].…”

Section: Introductionmentioning

confidence: 99%

West African Plants and Related Phytocompounds with Anti‐Multidrug‐Resistance Activity

Witabouna

Kagoyire

2008

New Strategies Combating Bacterial Infection

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Diseases due to multidrug resistant (MDR) bacteria have become a major health problem in developing as well as developed countries. Therapy of bacterial infections is a frequent problem due to the emergence of bacterial strains resistant to numerous antibiotics. In many west African countries, the prevalence of MDR bacteria is increasing despite the measures of control. This increase of MDR bacteria necessitates the search for new effective alternatives to replace antibacterial agents currently in use. In this instance, the plant kingdom is undoubtedly a valuable source for new antibiotics. Herbal medicine has been shown to have a genuine utility and rural population depens on it as primary health care. About 80% of the population in West Africa still use traditional medicine for treating diseases, both microbial and non-microbial origins. Ethnobotanical studies on west African medicinal plants has reasonably been done resulting into a collection of information which show that African medicinal plants could be source of leads compounds. A wide range of those medicinal plants have been studied for antibacterial activity against various bacteria, but few have included MDR bacteria. This chapter provides an overview of the West African plants and related phytocompounds with anti-MDR activity. An attempt has been made to summarize the information in order to highlight those promising medicinal plant in the treatment of diseases caused by multidrug resistant bacteria. The most promising are Erythrina senegalensis, Erythrina vogelii, Terminalia avicennioides, Momordica balsamina, Combretum paniculatum, Morinda lucida, Ocimum gratissimum and Trema guineensis. These plant species show a strong anti-MDR activity on MRSA, vancomycin resistant enterococci (VRE), Escherichia coli ESBL, Klebsiella pneumoniae ESBL and MDR-Salmonella typhi strains. The phytochemicals responsible for this activity are flavonoids, isoflavonoids, naphtoquinones, alkaloids, sesquiterpenoids, phenolic compounds and xanthones. Precise active principles, such as isowighteone, vogelin B and vogelin Cwith anti-MDR activity, have been isolated from Erythrina vogelii. The importance of MDR bacteria makes these data of special interest since many medicinal plants are used in traditional medicinal in places of West Africa where medical services are not in position to provide health care.New Strategies Combating Bacterial Infection. Edited by Iqbal Ahmad and Farrukh Aqil

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Place des bactériémies à Staphylococcus aureus au CHU de Fann à Dakar

Cited by 12 publications

References 19 publications

Antibiotic Resistance Pattern of Staphylococcus aureus and Associated Risk Factors in the Adamaoua and Far North Regions of Cameroon

Antibiotic Resistance Pattern of Staphylococcus aureus and Associated Risk Factors in the Adamaoua and Far North Regions of Cameroon

Methicillin-Resistant Staphylococcus aureus (MRSA): A major concern in the Northern Cameroon

West African Plants and Related Phytocompounds with Anti‐Multidrug‐Resistance Activity

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