Place du Hyalomatrix PA® au sein des substituts cutanés. À propos de dix cas

Perrot, Pierre; Dellière, V.; Brancati, Antonio; Duteille, Franck

doi:10.1016/j.anplas.2010.10.006

Cited by 9 publications

(3 citation statements)

References 31 publications

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“…This bioresorbable membrane was specifically addressed for the treatment of deep burns 30,31 and full-thickness wounds. 17,[32][33][34][35][36][37] It provides wound preparation to support the implantation of skin grafts. The 3-dimensional structure supports fibroblasts and extra-cellular matrix component invasion, leading to an ordered reconstruction of the dermal tissue.…”

Section: Discussionmentioning

confidence: 99%

“…This study reports our clinical experience with 15 cases of RFF donor site reconstruction with the use of dermal induction template followed by autologous STSG. This bioresorbable membrane was specifically addressed for the treatment of deep burns 30,31 and full-thickness wounds 17,32–37 . It provides wound preparation to support the implantation of skin grafts.…”

Section: Discussionmentioning

confidence: 99%

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Donor Site Wound Healing in Radial Forearm Flap

et al. 2021

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Radial forearm flap (RFF) is one of the most used flaps in reconstructive surgery. Despite its versatility and effectiveness, the donor site is affected by aesthetic and functional issues. In the group of techniques described to improve the donor site morbidity, dermal substitutes offer a valid approach in the wound management. A bilayered bioresorbable dermal substitute (Hyalomatrix) was used to provide the primary coverage of the RFF harvest site followed after 3 weeks by a split-thickness skin graft placement. In this study, 37 patients underwent RFF donor site reconstruction and subjected to a minimum follow-up of 1 year. The dermal substitute was applied on 15 patients, and their outcomes were compared with the data achieved by 22 patients submitted to immediate reconstruction with autologous full-thickness skin graft. Results were documented by digital photographs, the visual analog scale, the Vancouver Scar Scale, and the Disabilities of the Arm, Shoulder, and Hand questionnaire. Data were analyzed and compared through statistical analysis. Total wound coverage was achieved in 4 to 6 weeks, and no tendon impairments were reported in the dermal substitute group. In our experience, the use of the dermal substitute is a valuable mean to minimize RFF donor site morbidity with excellent functional and aesthetic outcomes.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Donor Site Wound Healing in Radial Forearm Flap

et al. 2021

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“…[49] A series of 10 cases was also reported in which loss of substance due to trauma, tumor or third-deep burns ( n = 5) was treated with Hyalomatrix, followed by a thin skin graft. [50] Good efficacy was reported in the short term and at 12 months. A flexible skin equivalent to that observed with collagen acellular dermal substitute as well as lack of adhesion of the tendon graft skin was observed which confirmed the dermal regeneration.…”

Section: Hyaluronic Acid Based Materialsmentioning

confidence: 99%

The use of hyaluronic acid based dressings to treat burns: A review

2014

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Deep cutaneous lesions such as burns, traumas or ulcers are all conditions characterized by a massive loss of dermis, bringing several important consequences. For the treatment of these conditions, the evolution of material science has made available new dressings based on natural and synthetic polymers. Hyaluronic acid (HA) is involved in many steps of the wound healing process, such as inflammation, granulation and re-epithelialization. In order to overcome the poor physical properties of the native polymer, such as solubility and rapid degradation, insoluble molecules starting from the natural compound were produced via esterification. Thanks to their improved structural properties, the dressings based on these hyaluronic acid derivatives represent a valuable option for the treatment of deep burns. This narrative monograph describes the development and the outcome of the use of these products in burns. The currently available clinical experience suggests that these HA medical devices represent a safe therapeutic method useful for the treatment of acute wounds.

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Limb trauma: the use of an advanced wound care device in the treatment of full-thickness wounds

Vaienti

Marchesi

Palitta

et al. 2013

Strategies in Trauma and Limb Reconstruction

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This is an observational case series of 15 patients with full-thickness traumatic wound defects treated with a dermal substitute. There were 8 male and 7 female patients with a mean age of 36.6 years. Eight patients had trauma to the lower limbs and 7 were of the upper limbs, with the average lesion size 104.4 cm2 (range 6–490 cm2). The time to complete healing had a mean average time of 26.8 days (range 16–60 days). All patients went on to successful repair with 6 patients requiring a second application of the substitute and 5 patients needing split thickness skin grafts. Infection was recorded in one patient.

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Place du Hyalomatrix PA® au sein des substituts cutanés. À propos de dix cas

Cited by 9 publications

References 31 publications

Donor Site Wound Healing in Radial Forearm Flap

Donor Site Wound Healing in Radial Forearm Flap

The use of hyaluronic acid based dressings to treat burns: A review

Limb trauma: the use of an advanced wound care device in the treatment of full-thickness wounds

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