The article presents the results of a participatory research process based on the arts, which sought to incorporate art and creativity in seven units of a high-complexity university hospital, for support at the end of life and bereavement. This was done through the provision of kits with materials with creative potential and the development of awareness and creation workshops with health and administrative staff, patients, and family members. The process was produced through participant observation and field diaries. Informal, semi-structured interviews and a discussion group were also conducted to identify the main barriers and facilitators of the proposal. We conclude that, in order to integrate this type of resources and for care centered on the person and families, health services require deep transformations that include death as a significant experience, giving space to their own mourning and emotions, which would reduce Fatigue due to inflammation is very frequent in health personnel confronted with death in a systematic way. The project was approved by the respective ethics committee.