Placenta with Old, Diffuse Infarction that Was Difficult to Differentiate from a Placental Tumor

Abstract

Placental lesions, including placental infarction, are associated with fetal and neonatal mortality and morbidity. We present a case of fetal growth restriction associated with an old, diffuse placental infarction. Because the placenta had only a single viable cotyledon, the others being atrophic, the lesion appeared to be a placental tumor on prenatal ultrasonography. The patient did not have pregnancyinduced hypertension. At 31 weeks of gestation, a cesarean delivery was performed because of fetal growth arrest and breech presentation. A small-for-gestational age infant was delivered with Apgar scores of 8 at both 1 and 5 minutes, and the infant had cleft palate and cleft lips. Pathological examination of the placenta revealed an old, diffuse infarction without neoplastic change. In cases in which a placental tumor causing fetal growth restriction is strongly suspected, diffuse placental infarction should be considered as part of the differential diagnosis, because placental tumors are associated with poor maternal prognosis. (J Nippon Med Sch 2015; 82: 156 158)

Pathological Findings in Fetuses Terminated for Suspected Lower Urinary Tract Obstruction: Experience From a High-Risk Fetal Center in Canada

“…23,24 Acute marginal villous infarcts, seen in 1 LUTO case, are also common pathologies associated with fetal mortality in premature fetuses. 25,26 Hence, these findings should likely be attributed to pregnancy termination and preterm delivery, and not to the underlying fetal anomaly.…”

Pathologic examination of the placenta and its benefits in treatment plan or follow-up of patients: a cross-sectional study

“…Placental lesions, including placental infarction, are associated with fetal and neonatal mortality, and complications, and are one of the most common placental complications. When premature, focal, or diffuse infarction occurs, it is associated with severe preeclampsia, IUGR, and even fetal death [ 15 ].…”

Placental infarction with fetal ischemic stroke detected via MRI: a case report and literature review

“…Factors underlying this condition can include pregnancy-related hypertension [2] , eclampsia, lupus anticoagulation, placental abruption, varicella, rubella, and other viral infections [3] . Although color Doppler ultrasound is the preferred examination method used when evaluating circulation within the placenta to detect any abnormalities, the diagnostic sensitivity of this technique is very low owing to differences in cell numbers, brin deposition, calci cation, and bleeding such that just 10% of placental infarction cases are detected before birth [4] .…”