Placental Chorioangioma with Nonimmune Hydrops Fetalis

Abstract

A 38-year-old woman was found to have a large placental chorioangioma. The fetus was studied using ultrasound. The pregnancy became complicated by hydrops fetalis, polyhydramnios, and abruptio placenta. The infant delivered at 29 weeks' gestational age. The neonatal course was complicated by nonimmune hydrops fetalis, respiratory distress syndrome, anemia, pulmonary hemorrhage, intraventricular hemorrhage, necrotizing enterocolitis, and bronchopulmonary dysplasia. The infant was discharged home with breastfeeding and off oxygen at 50 days of life. This case represents the multidisciplinary approach to the pregnancy complicated by a large placental chorioangioma and the resulting premature neonate with nonimmune hydrops fetalis.

Reverse diastolic flow of the fetal middle cerebral artery associated with placental chorangiomatosis and asymptomatic concealed placental abruption

“…The neonate manifested cardiomegaly, microangiopathic hemolytic anemia, and thrombocytopenia, which resolved over time, and was attributed to diffuse placental chorangiomatosis [12] . Similarly, fetal anemia has been reported in association with placental chorioangioma [13 , 14] .…”

Radio frequency ablation for the intrauterine treatment of giant placental chorioangioma associated with fetal compromise: A case report

“…Some cases reported that fetal cardiac insufficiency caused by placental chorioangioma separated from the adverse hemodynamic circulation states after timely termination of pregnancy, and neonatal cardiac function gradually recovered. However, at the same time, preterm infants often face a variety of complications after termination of pregnancy, and the long-term prognosis has not been reported (Merry-Sperry et al, 2018;Willis, Ferguson, & Soydemir, 2019). The gestational age of the gravida in this case is small.…”