Placental histology following assisted hatching in fresh transfer cycles

Herman, Hadas Ganer; Volodarsky‐Perel, Alexander; Nu, Tuyet Nhung Ton; Cui, Yong; Shaul, Jonathan; Dahan, Michael H.

doi:10.1007/s00404-022-06648-4

Cited by 3 publications

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They further reported that inadequate AH can impede complete hatching during the incubation process, therefore causing problems with subsequent embryonic development, which can lead to placental malformation, miscarriage, or twin pregnancies [16]. Herman et al also reported that since hatching is performed over the trophectoderm cells, which will subsequently develop into the placenta, the act of AH may be hypothesized to affect these cells and thus lead to increased rates of bilobated placentas [17].…”

Section: Discussionmentioning

confidence: 99%

The Impact of Assisted Reproductive Technology on Umbilical Cord Insertion: Increased Risk of Velamentous Cord Insertion in Singleton Pregnancies Conceived through ICSI

Fukuda,

Hamuro,

Kitada

et al. 2023

Medicina

View full text Add to dashboard Cite

Background and Objectives: Vasa previa (VP) is a significant perinatal complication that can have serious consequences for the fetus/neonate. Velamentous cord insertion (VCI) is a crucial finding in prenatal placental morphology surveillance as it is indicative of comorbid VP. Assisted reproductive technology (ART) has been identified as a risk factor for VCI, so identifying risk factors for VCI in ART could improve VP recognition. This study aims to evaluate the displacement of umbilical cord insertion (CI) from the placental center and to examine the relationship between the modes of conception. Materials and Methods: We conducted a retrospective study at the Obstetrics Department of Osaka Metropolitan University Hospital in Japan between May 2020 and June 2022. The study included a total of 1102 patients who delivered after 22 weeks of gestation. They were divided into three groups: spontaneous pregnancy, conventional in vitro fertilization (cIVF), and in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI). We recorded patient background information, perinatal complications, perinatal outcomes, and a numerical “displacement score”, indicating the degree of separation between umbilical CI and the placental center. Results: The displacement score was significantly higher in the cIVF and IVF/ICSI groups compared with the spontaneous conception group. Additionally, the IVF/ICSI group showed a significantly higher displacement score than the cIVF group. Conclusions: Our study provides the first evidence that the methods of ART can affect the location of umbilical CI on the placental surface. Furthermore, we found that IVF/ICSI may contribute to greater displacement of CI from the placental center.

show abstract

Section: Discussionmentioning

confidence: 99%

The Impact of Assisted Reproductive Technology on Umbilical Cord Insertion: Increased Risk of Velamentous Cord Insertion in Singleton Pregnancies Conceived through ICSI

Fukuda,

Hamuro,

Kitada

et al. 2023

Medicina

View full text Add to dashboard Cite

show abstract

Assisted reproductive technology-associated risk factors for retained products of conception

Jwa,

Takahashi,

Tamaru

et al. 2024

Fertility and Sterility

View full text Add to dashboard Cite

Assisted reproductive technology-associated risk factors for placenta accreta spectrum after vaginal delivery

Jwa,

Tamaru,

Takamura

et al. 2024

Sci Rep

View full text Add to dashboard Cite

This study aimed to investigate assisted reproductive technology (ART) factors associated with placenta accreta spectrum (PAS) after vaginal delivery. This was a registry-based retrospective cohort study using the Japanese national ART registry. Cases of live singleton infants born via vaginal delivery after single embryo transfer (ET) between 2007 and 2020 were included (n = 224,043). PAS was diagnosed in 1412 cases (0.63% of deliveries), including 1360 cases (96.3%) derived from frozen-thawed ET cycles and 52 (3.7%) following fresh ET. Among fresh ET cycles, assisted hatching (AH) (adjusted odds ratio [aOR], 2.5; 95% confidence interval [CI] 1.4–4.7) and blastocyst embryo transfer (aOR, 2.2; 95% CI 1.3–3.9) were associated with a significantly increased risk of PAS. For frozen-thawed ET cycles, hormone replacement cycles (HRCs) constituted the greatest risk factor (aOR, 11.4; 95% CI 8.7–15.0), with PAS occurring in 1.4% of all vaginal deliveries following HRC (1258/91,418 deliveries) compared with only 0.11% following natural cycles (55/47,936). AH was also associated with a significantly increased risk of PAS in frozen-thawed cycles (aOR, 1.2; 95% CI 1.02–1.3). Our findings indicate the need for additional care in the management of patients undergoing vaginal delivery following ART with HRC and AH.

show abstract

Placental histology following assisted hatching in fresh transfer cycles

Cited by 3 publications

References 20 publications

The Impact of Assisted Reproductive Technology on Umbilical Cord Insertion: Increased Risk of Velamentous Cord Insertion in Singleton Pregnancies Conceived through ICSI

The Impact of Assisted Reproductive Technology on Umbilical Cord Insertion: Increased Risk of Velamentous Cord Insertion in Singleton Pregnancies Conceived through ICSI

Assisted reproductive technology-associated risk factors for retained products of conception

Assisted reproductive technology-associated risk factors for placenta accreta spectrum after vaginal delivery

Contact Info

Product

Resources

About