Placental mesenchymal dysplasia associated with trisomy 13: Sonographic findings

Müngen, Ercüment; Dündar, Özgür; Muhçu, Murat; Haholu, Aptullah; Tunca, Yusuf

doi:10.1002/jcu.20454

Cited by 24 publications

(14 citation statements)

References 13 publications

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“…Of the 110 cases reviewed, 44 cases of PMD showed multicystic placenta in antenatal ultrasound scan [1,2,3,5,7,9,10,11,12,13,16,18,19,20,22,23,26,27,28,29,30,31,32,33,34,41,42,43,44,45,46,47,48]. Figure 5 represents the gestational age at which the multicystic pattern was identified in the 44 cases and the current case.…”

Section: Resultsmentioning

confidence: 99%

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Placental Mesenchymal Dysplasia: Chronological Observation of Placental Images during Gestation and Review of the Literature

Ohira¹,

Ookubo²,

Tanaka³

et al. 2013

Gynecol Obstet Invest

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Placental mesenchymal dysplasia (PMD) is characterized by multiple hypoechoic vesicles which are similar to molar changes in the placenta; however, the process of such morphological changes of PMD during pregnancy has not been fully understood. We performed a review of all PMD cases published in English and identified 49 articles including 110 cases. With regard to the gestational age at which the multicystic pattern was seen,approximately 70% of cases were diagnosed at 13-20 weeks of gestation. Another characteristic feature of PMD is varicose dilation of fetal chorionic vessels. As many as 90% of cases were diagnosed as placenta with dilated fetal chorionic vessels in the third trimester. We also report a case of PMD which was found at 10 weeks of gestation according to ultrasonic molar patterns. Serial observations of the placenta using ultrasound and magnetic resonance imaging revealed that multicystic lesions became smaller after 23 weeks. In contrast, dilated placental vessels on the fetal side became apparent at 38 weeks. The present review highlights that placental vesicular lesions of PMD may precede dilation of fetal chorionic vessels during pregnancy. It also indicates the potential of a gradual reduction in size of PMD's placental vesicular lesions by serial study of placental images.

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Section: Resultsmentioning

confidence: 99%

“…All articles without an abstract or with unavailable full text were excluded. We identified 49 articles including 110 cases of PMD [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49]. …”

Section: Literaturementioning

confidence: 99%

Placental Mesenchymal Dysplasia: Chronological Observation of Placental Images during Gestation and Review of the Literature

Ohira¹,

Ookubo²,

Tanaka³

et al. 2013

Gynecol Obstet Invest

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“…[9,10] INVESTIGATION: Ultrasonography is the imaging investigation of choice for hydatidiform mole. The established roles for sonography include the following; [11,12,13,14,15,16] 1. Initial diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Partial Hydatidiform Mole With a Live Fetus: A Rare Entity

Kakumanu¹,

G²,

M³

et al. 2015

jemds

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“…Chromosomal abnormalities may be found in a few fetuses, but most are karyotypically and phenotypically normal females. Placental mesenchymal dysplasia may be associated with chromosomal abnormalities such as trisomy 13, Klinefelter syndrome, triploidy and Xp deletion [6,7]. Rare cases of fetal congenital adrenal hyperplasia, vascular hamartoma, and hepatic mesenchymal hamartoma have been described [8].…”

Section: Discussionmentioning

confidence: 99%

Placental mesenchymal dysplasia associated with severe preeclampsia: A case report

Lee

Kim

et al. 2011

Korean J Obstet Gynecol

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Placental mesenchymal dysplasia (PMD) is a relatively recently recognized, rare placental vascular anomaly characterized by placentomegaly and grapelike vesicles that may coexist with a normal fetus. Ultrasonography performed at 16 weeks of gestation revealed multiple cysts in the placenta along with a morphologically normal fetus. At 24 weeks of gestational age, severe preeclampsia symptoms were seen. And sonographically intrauterine growth restriction (IUGR) and oligohydroamnios were noted. Based on the diagnosis of severe preeclampsia, termination of pregnancy was done. After termination, histopathologic examination of the placenta showed numerous grape-like cystic vesicles throughout the entire placenta and absence of trophoblastic proliferation and pseudoinclusions. We have described a pregnancy complicated with PMD associated with mid-trimester severe preeclampsia, IUGR and oligohydroamnios.

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Placental mesenchymal dysplasia associated with trisomy 13: Sonographic findings

Cited by 24 publications

References 13 publications

Placental Mesenchymal Dysplasia: Chronological Observation of Placental Images during Gestation and Review of the Literature

Placental Mesenchymal Dysplasia: Chronological Observation of Placental Images during Gestation and Review of the Literature

Partial Hydatidiform Mole With a Live Fetus: A Rare Entity

Placental mesenchymal dysplasia associated with severe preeclampsia: A case report

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