Plant-Derived Polysaccharides Regulated Immune Status, Gut Health and Microbiota of Broilers: A Review

Abstract

In modern intensive breeding system, broilers are exposed to various challenges, such as diet changes and pathological environment, which may cause the increase in the incidence rate and even death. It is necessary to take measures to prevent diseases and maintain optimal health and productivity of broilers. With the forbidden use of antibiotics in animal feed, polysaccharides from plants have attracted much attention owing to their lower toxicity, lower drug resistance, fewer side effects, and broad-spectrum antibacterial activity. It had been demonstrated that polysaccharides derived from plant exerted various functions, such as growth promotion, anti-inflammation, maintaining the integrity of intestinal mucosa, and regulation of intestinal microbiota. Therefore, the current review aimed to provide an overview of the recent advances in the impacts of plant-derived polysaccharides on anti-inflammation, gut health, and intestinal microbiota community of broilers in order to provide a reference for further study on maintaining the integrity of intestinal structure and function, and the related mechanism involved in the polysaccharide administration intervention.

Antrodia cinnamomea polysaccharide improves liver antioxidant, anti-inflammatory capacity, and cecal flora structure of slow-growing broiler breeds challenged with lipopolysaccharide

“…It is used in folk medicine as a cure for liver problems and a number of active substances can be found in Antrodia cinnamomea such as polysaccharides. Natural polysaccharides have various functions such as growth promotion, anti-inflammation, maintenance of intestinal mucosal integrity, regulation of intestinal flora (1)(2)(3)(4)(5). It has been reported that health benefits of Antrodia cinnamomea have antioxidants properties due to its polysaccharide, polyphenol and triterpenoid contents (6).…”

Progress of Studies on Plant-Derived Polysaccharides Affecting Intestinal Barrier Function in Poultry

“…However, different sources of polysaccharides have different probiotic effects on intestinal microbiota [ 57 ]. Besides, since most plant-derived polysaccharides cannot be digested and degraded in the stomach and small intestine, they are degraded by bacteria in the large intestine and then biotransformed to exert their biological functions [ 58 ]. Furthermore, metabolomic analysis of intestinal contents revealed that Astragalus polysaccharides might influence butyrate metabolism, alanine, aspartate and glutamate metabolism, the conversion of pentose and glucuronide, and D-glutamine and D-glutamate metabolism [ 59 ].…”

Evaluation of the Efficacy of Xyloglucan, Pea Protein and Opuntia ficus-indica Extract in a Preclinical Model of Psoriasis

“…Topical corticosteroids (CS) represent the most commonly prescribed treatment for psoriasis, with dexamethasone (DXM) being one of the recommended treatments. Despite the known efficacy of conventional therapies to decrease signs and symptoms severity, side effects may appear, such as atrophy, development of striae, steroid rosacea and skin bacterial superinfections [ 6 ]. Indeed, novel therapeutical strategies for psoriasis treatment could be represented by alternative approaches.…”

“…Indeed, novel therapeutical strategies for psoriasis treatment could be represented by alternative approaches. In recent years, naturally derived ingredients such as polysaccharides [ 6 , 7 ], extracts [ 8 ] and essential oils [ 9 ] have gained much attention for their health benefits and tolerability. Tamarind seed gum (Xyloglucan) is a hemicellulose extracted from the seed of the tamarind tree, Tamarindus indica.…”