Plant Metabolism Adjustment in Exogenously Applied Ethylene under Stress

Niharika, .; Singh, Narsingh Bahadur; Singh, Arun Kumar; Khare, Shubhra

doi:10.1002/9781119744719.ch10

Cited by 1 publication

(1 citation statement)

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“…The process of developing inactivated COVID-19 vaccines involves killing the coronavirus using chemical or physical means, while preserving its antigenic structure. This process renders the virus non-infectious, but still capable of stimulating the body's immune response and preventing infection [10]. It involves several key steps, such as virus isolation and propagation, inactivation, purification, formulation, preclinical testing, clinical trials, regulatory approval, and finally, production and distribution (Figure 1).…”

Section: The Inactivated Vaccine Development Processmentioning

confidence: 99%

A Review of Inactivated COVID-19 Vaccine Development in China: Focusing on Safety and Efficacy in Special Populations

Sun

Wang

et al. 2023

Vaccines

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The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been widespread globally, and vaccination is critical for preventing further spread or resurgence of the outbreak. Inactivated vaccines made from whole inactivated SARS-CoV-2 virus particles generated in Vero cells are currently the most widely used COVID-19 vaccines, with China being the largest producer of inactivated vaccines. As a result, the focus of this review is on inactivated vaccines, with a multidimensional analysis of the development process, platforms, safety, and efficacy in special populations. Overall, inactivated vaccines are a safe option, and we hope that the review will serve as a foundation for further development of COVID-19 vaccines, thus strengthening the defense against the pandemic caused by SARS-CoV-2.

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Section: The Inactivated Vaccine Development Processmentioning

confidence: 99%