Chemicals first used in agriculture to control pant diseases were inorganic fungicides such as elemental sulfur, lime sulfur, and copper fungicides, including Bordeaux mixture. Those fungicides are primarily applied to cover the surface of the plants to protect them from various plant pathogens. They are, therefore, broad‐spectrum surface protectants and have been used since the nineteenth century. However, their use has been limited because of their lower level of effectiveness, risk of their toxicity to the plants, and lack of compatibility in use with other fungicides and insecticides.