Plant molecules and their influence on health and female reproduction

Sirotkin, Alexander V.; Kolesárová, Adriana

doi:10.1016/b978-0-12-824292-6.00004-0

Cited by 4 publications

(2 citation statements)

References 503 publications

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“…This biologically active molecule can impact a wide range of both non-reproductive and reproductive processes, offering potential therapeutic benefits for various disorders. Among natural antioxidants, rutin is considered to be one of the most potent within its known class [70,71]. In the present study, BWF contained 246.93 ± 0.75 mg/kg rutin.…”

Section: Individual Polyphenols Of Composite Flours and Cookies Deter...mentioning

confidence: 69%

Gluten-Free Cookies Enriched with Baobab Flour (Adansonia digitata L.) and Buckwheat Flour (Fagopyrum esculentum)

Dossa,

Dragomir,

Plustea

et al. 2023

Applied Sciences

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To provide people with celiac disease with nutrient-rich gluten-free foods, this study aimed to produce cookies based on buckwheat and baobab flours, which were then subjected to nutritional, phytochemical, and sensory analyses. Results demonstrate that baobab flour (BF) and buckwheat flour (BWF) work together to enhance the nutritional properties of the cookies, in that nutrients that BWF is deficient in, BF provides sufficiently, and vice versa. BF is rich in minerals and carbohydrates, while BWF contains comparatively higher fat and protein levels. As for macro- and micro-elements, potassium (K) is the predominant macro-element in BF and BWF, with 13,276.47 ± 174 mg/kg and 1255.35 ± 58.92 mg/kg, respectively. The polyphenol content is higher in BF than BWF, at 629.7 ± 0.35 mg/100 g as opposed to 283.87 ± 0.06 mg/100 g. Similarly, the total flavonoid content and antioxidant activity of BF was greater than that of BWF, while BF exhibited 213.13 ± 0.08 mg/100 g and 86.62 ± 0.04%, in contrast to BWF, which had 125.36 ± 1.12 mg/100 g and 79.72 ± 0.01%, respectively. BF significantly enhanced the phytochemical composition of the cookies, with the richest sample being BBC3 containing 30% baobab. Buckwheat and baobab have the most abundant phenolic compounds of rutin and epicatechin, respectively. About the analysis of sensory attributes of the cookies, the partial substitution of BWF by BF of up to 20% (BWF3) significantly increased the scores for all attributes. Indeed, the appearance (physical aspect of the cookie: whether it is firm or not) and color (influence of baobab addition on cookie coloration) of the cookies were significantly improved with the addition of BF of up to 20%, but above 20% they were less appreciated. Similarly, up to 20% BF, the texture, flavor, and overall acceptability of the cookies were significantly improved. Taste, on the other hand, was not significantly improved, maybe due to the acidic taste provided by the baobab.

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Section: Individual Polyphenols Of Composite Flours and Cookies Deter...mentioning

confidence: 69%

Gluten-Free Cookies Enriched with Baobab Flour (Adansonia digitata L.) and Buckwheat Flour (Fagopyrum esculentum)

Dossa,

Dragomir,

Plustea

et al. 2023

Applied Sciences

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“…Natural progesterone is isolated from diosgenin, a sterol extracted from the Dioscorea species of yam. Intake of diosgenin may affect serum progesterone levels ( 39 ). Given that progesterone supplementation does impact the outcome in frozen embryo transfer, it is possible that patients who take diosgenin, especially without notifying their infertility providers, may have altered progesterone serum levels or altered implantation window or both and thus may end up with lower pregnancy rates during either a programmed or natural frozen embryo transfer ( 40 ).…”

Section: Discussionmentioning

confidence: 99%

Herbal supplement use among reproductive-aged women in an academic infertility practice

Friedman¹,

Sheeder²,

Lazorwitz³

et al. 2023

F&S Reports

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The influence of apigenin on cellular responses to radiation: From protection to sensitization

Monadi,

Mohajer,

Soltani

et al. 2024

BioFactors

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Apigenin, a dietary flavonoid, has gained increasing attention for its potential therapeutic applications in radiation protection and radiosensitization. Ionizing radiation (IR) can harm healthy cells, but as radiotherapy remains crucial in cancer treatment. Owing to the remarkable application of radiotherapy in the treatment of cancers, it is vital to protect healthy cells from radiation hazards while increasing the sensitivity of cancer cells to radiation. This article reviews the current understanding of apigenin's radioprotective and radiosensitive properties with a focuses on the involved signaling pathways and key molecular targets. When exposed to irradiation, apigenin reduces inflammation via cyclooxygenase‐2 inhibition and modulates proapoptotic and antiapoptotic biomarkers. Apigenin's radical scavenging abilities and antioxidant enhancement mitigate oxidative DNA damage. It inhibits radiation‐induced mammalian target of rapamycin activation, vascular endothelial growth factor (VEGF), matrix metalloproteinase‐2 (MMP), and STAT3 expression, while promoting AMPK, autophagy, and apoptosis, suggesting potential in cancer prevention. As a radiosensitizer, apigenin inhibits tumor growth by inducing apoptosis, suppressing VEGF‐C, tumor necrosis factor alpha, and STAT3, reducing MMP‐2/9 activity, and inhibiting cancer cell glucose uptake. Cellular and animal studies support apigenin's radioprotective and anticancer potential, making it a potential candidate for further research. Investigation into apigenin's therapeutic efficacy in diverse cancer types and radiation damage is essential.

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Plant molecules and their influence on health and female reproduction

Cited by 4 publications

References 503 publications

Gluten-Free Cookies Enriched with Baobab Flour (Adansonia digitata L.) and Buckwheat Flour (Fagopyrum esculentum)

Gluten-Free Cookies Enriched with Baobab Flour (Adansonia digitata L.) and Buckwheat Flour (Fagopyrum esculentum)

Herbal supplement use among reproductive-aged women in an academic infertility practice

The influence of apigenin on cellular responses to radiation: From protection to sensitization

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