Plant or Animal-Based or PLADO Diets: Which Should Chronic Kidney Disease Patients Choose?

A number of studies in the general population showed that healthy dietary patterns, such as the Mediterranean Diet, can improve or prevent the development of several chronic diseases and are associated with a significant reduction in all-cause and cardiovascular mortality. The Mediterranean diet may also have favorable effects for the prevention of chronic kidney disease (CKD), but no evidence of renoprotection exists in CKD patients. The Mediterranean Renal (MedRen) diet is an adaptation of the Mediterranean diet recommendations comprising a quantitative reduction in the RDA values of protein, salt and phosphate intake for the general population. Hence, MedRen supplies 0.8 g/Kg of protein, 6 g of salt and less than 800 mg of phosphate daily. Obviously, there is a preference for products of plant origin, which contain more alkali, fibers, unsaturated fatty acids than animal-based food. The MedRen diet can be implemented easily in mild-to-moderate stages of CKD with good results, both in terms of adherence to prescriptions and metabolic compensation. In our opinion, it should be the first step of CKD stage 3 nutritional management. This paper describes the features and reports our experience in the implementation of the MedRen diet as an early nutritional approach to CKD.

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“…The MedRen diet meets the characteristics described for the plant-dominant (PLADO) diet particularly suitable for patients with CKD [39,40].…”

Section: The Mediterranean Renal Dietmentioning

confidence: 99%

Mediterranean Dietary Pattern Adjusted for CKD Patients: The MedRen Diet

2023

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“…According to Global Burden of Disease Study, dietary risk factors are major contributors to millions of deaths, leading to higher mortality rates than well-known risk factors such as smoking [ 20 ]. Lifestyle interventions, such as healthy nutritional habits, proved to be effective in reducing cardiovascular risk factors in the general population [ 21 ]. High intake of sodium and sugar and a low intake of whole grains, vegetables, and fruits can cause type 2 diabetes mellitus, hypertension, cardiovascular disease, cancer, and CKD [ 22 ].…”

Section: Food For Ckd Patientsmentioning

confidence: 99%

“…The foundation of nutrition intervention in CKD was laid for decades on a low-protein diet to slow progression and on restriction of plant foods, such as vegetables and fruits, to prevent hyperkalemia. Lately, this paradigm has changed, and the plant-dominant low-protein (PLADO) diets seem to have become a better choice for patients with CKD [ 21 ]. In a sub-analysis of the NHANES III study on 14,000 participants patients with a glomerular filtration rate < 60 mL/min, a diet with a higher proportion of protein from plant sources was associated with lower mortality, probably due to lower production of uremic toxins and lower serum phosphorus levels [ 30 ].…”

Section: Protein Intake and Vascular Calcification In Ckdmentioning

confidence: 99%

Food to Prevent Vascular Calcification in Chronic Kidney Disease

Moldovan,

Rusu,

Potra

et al. 2024

Nutrients

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Vascular calcification (VC) is a consequence of chronic kidney disease (CKD) which is of paramount importance regarding the survival of CKD patients. VC is far from being controlled with actual medication; as a result, in recent years, diet modulation has become more compelling. The concept of medical nutritional therapy points out the idea that food may prevent or treat diseases. The aim of this review was to evaluate the influence of food habits and nutritional intervention in the occurrence and progression of VC in CKD. Evidence reports the harmfulness of ultra-processed food, food additives, and animal-based proteins due to the increased intake of high absorbable phosphorus, the scarcity of fibers, and the increased production of uremic toxins. Available data are more supportive of a plant-dominant diet, especially for the impact on gut microbiota composition, which varies significantly depending on VC presence. Magnesium has been shown to prevent VC but only in experimental and small clinical studies. Vitamin K has drawn considerable attention due to its activation of VC inhibitors. There are positive studies; unfortunately, recent trials failed to prove its efficacy in preventing VC. Future research is needed and should aim to transform food into a medical intervention to eliminate VC danger in CKD.

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“…La DBP se define como un enfoque alimentario que se centra en el consumo de alimentos de origen vegetal, como frutas, verduras, granos enteros, legumbres y nueces, y limita o excluye los alimentos de origen animal (2) . Este enfoque ha sido objeto de numerosos estudios que han demostrado sus beneficios para la salud en general, incluyendo la reducción del riesgo de enfermedades crónicas como la diabetes, la obesidad y las enfermedades cardiovasculares.…”

Section: Introductionunclassified

Plantas para tus riñones: una revisión narrativa sobre la dieta basada en plantas y la enfermedad renal crónica

Ponce,

Mariños

et al. 2024

Rev. Nutr. Clin. Metab.

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La enfermedad renal crónica (ERC) es una afección prevalente que afecta a millones de personas en todo el mundo. Los tratamientos convencionales a menudo no proporcionan recuperación renal, lo que lleva a un creciente interés en intervenciones dietéticas alternativas. Las dietas basadas en plantas han ganado atención debido a su potencial para aliviar las complicaciones relacionadas con esta patología y promover la salud en general. Este artículo examina la literatura sobre dietas basadas en plantas en el manejo de la ERC en tratamiento conservador, y destaca sus beneficios potenciales en el control de la presión arterial, la reducción de la inflamación, la mitigación del estrés oxidativo y la mejora del perfil lipídico. También discute los desafíos y las consideraciones asociados con la adopción de este tipo de regímenes alimentarios, incluidas las posibles deficiencias de nutrientes y los ajustes de medicamentos. El artículo enfatiza la importancia de los enfoques dietéticos individualizados considerando factores como la etapa de la ERC, las comorbilidades y los requisitos nutricionales. También destaca el papel de los profesionales nutricionistas en la educación y orientación de estos pacientes hacia patrones dietéticos apropiados basados en plantas. Se necesita investigación adicional para dilucidar la composición óptima y la viabilidad de las dietas basadas en plantas en el tratamiento de individuos que padecen ERC en manejo conservador.

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Plant or Animal-Based or PLADO Diets: Which Should Chronic Kidney Disease Patients Choose?

Cited by 10 publications

References 81 publications

Mediterranean Dietary Pattern Adjusted for CKD Patients: The MedRen Diet

Mediterranean Dietary Pattern Adjusted for CKD Patients: The MedRen Diet

Food to Prevent Vascular Calcification in Chronic Kidney Disease

Plantas para tus riñones: una revisión narrativa sobre la dieta basada en plantas y la enfermedad renal crónica

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