Plant Responses to Abiotic Stress Regulated by Histone Deacetylases

Luo, Ming; Cheng, Kai; Yang, Xu; Yang, Songguang; Wu, Keqiang

doi:10.3389/fpls.2017.02147

Cited by 86 publications

(68 citation statements)

References 64 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A similar expression pattern as for HDA3 was observed for HD2C. HD2A, HD2C, and HD2D interact with HDA6 and HDA19 in multiprotein complexes (Luo et al, 2017), and HD2C also interacts with BRAHMA, a chromatin remodeler involved in negative regulation of heat-responsive genes (Buszewicz et al, 2016). HD2C and the WD-40-repeat containing protein HOS15 interact before binding to the promoters of the cold-responsive genes COR15A and COR47.…”

Section: Histone Variants Respond Differentially and Strongly To Coldsupporting

confidence: 62%

“…Hyper-acetylation of histone H3K9 in promoter regions of DREB1, a main regulator of cold response, was observed in rice and was decreased again when plants were returned to control temperatures, suggesting that deacetylation keeps the gene in an off-state in the absence of cold (Roy et al, 2014). Recently, epigenetic changes involved in cold response were reviewed by different authors (Baulcombe and Dean, 2014;Kim et al, 2015;Asensi-Fabado et al, 2017;Banerjee et al, 2017;Luo et al, 2017;Friedrich et al, 2019). Furthermore, epigenetic changes that establish environmental memory in plants have been described (He and Li, 2018).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Transcriptional and Post-Transcriptional Regulation and Transcriptional Memory of Chromatin Regulators in Response to Low Temperature

et al. 2020

View full text Add to dashboard Cite

Chromatin regulation ensures stable repression of stress-inducible genes under nonstress conditions and transcriptional activation and memory of stress-related genes after stress exposure. However, there is only limited knowledge on how chromatin genes are regulated at the transcriptional and post-transcriptional level upon stress exposure and relief from stress. We reveal that the repressive modification histone H3 lysine 27 trimethylation (H3K27me3) targets genes which are quickly activated upon cold exposure, however, H3K27me3 is not necessarily lost during a longer time in the cold. In addition, we have setup a quantitative reverse transcription polymerase chain reactionbased platform for high-throughput transcriptional profiling of a large set of chromatin genes. We find that the expression of many of these genes is regulated by cold. In addition, we reveal an induction of several DNA and histone demethylase genes and certain histone variants after plants have been shifted back to ambient temperature (deacclimation), suggesting a role in the memory of cold acclimation. We also re-analyze large scale transcriptomic datasets for transcriptional regulation and alternative splicing (AS) of chromatin genes, uncovering an unexpected level of regulation of these genes, particularly at the splicing level. This includes several vernalization regulating genes whose AS may result in cold-regulated protein diversity. Overall, we provide a profiling platform for the analysis of chromatin regulatory genes and integrative analyses of their regulation, suggesting a dynamic regulation of key chromatin genes in response to low temperature stress.

show abstract

Section: Histone Variants Respond Differentially and Strongly To Coldsupporting

confidence: 62%

Section: Introductionmentioning

confidence: 99%

Transcriptional and Post-Transcriptional Regulation and Transcriptional Memory of Chromatin Regulators in Response to Low Temperature

et al. 2020

View full text Add to dashboard Cite

show abstract

“…In total, 16 Arabidopsis HDAC genes have been identified, of which 10 belong to the RPD3 superfamily, four to the HD2 family, and two to the SIR2 family (Pandey et al ., ). HDACs have been shown to regulate many aspects of plant development and responses to environmental changes (Luo et al ., ). For instance, HDA19, a RPD3 family member, is required for normal embryo development, photomorphogenesis, and light‐regulated gene expression (Benhamed et al ., ; Long et al ., ), and is involved in diverse stress responses (Zhou et al ., ; Kim et al ., ; Choi et al ., ).…”

Section: Introductionmentioning

confidence: 97%

Arabidopsis histone deacetylase HDA15 directly represses plant response to elevated ambient temperature

et al. 2019

View full text Add to dashboard Cite

Elevated ambient temperatures affect plant growth and substantially impact biomass and crop yield. Recent results have indicated that chromatin remodelling is critical in plant thermal responses but how histone modification dynamics affects plant thermal response has not been clearly demonstarted. Here we show that Arabidopsis histone deacetylase genes HDA9, HDA15 and HDA19 play distinct roles in plant response to elevated ambient temperature. hda9 and hda19 mutants showed a warm-temperature-insensitive phenotype at 27°C, whereas hda15 plants displayed a constitutive warm-temperature-induced phenotype at 20°C and an enhanced thermal response at 27°C. The hda19 mutation led to upregulation of genes mostly related to stress response at both 20 and 27°C. The hda15 mutation resulted in upregulation of many warm temperature-responsive as well as metabolic genes at 20 and 27°C, while hda9 led to differential expression of a large number of genes at 20°C and impaired induction of warm-temperature-responsive genes at 27°C. HDA15 is associated with thermosensory mark genes at 20°C and that the association is decreased after shifting to 27°C, indicating that HDA15 is a direct repressor of plant thermal-responsive genes at normal temperature. In addition, as hda9, the hda15 mutation also led to upregulation of many metabolic genes and accumulation of primary metabolites. Furthermore, we show that HDA15 interacts with the transcription factor HFR1 (long Hypocotyl in Far Red1) to cooperatively repress warm-temperature response. Our study demonstrates that the histone deacetylases target to different sets of genes and play distinct roles in plant response to elevated ambient temperature.

show abstract

“…More specifically, the mechanism by which histone acetylation optimizes plant response to environmental stresses through HDACs has been elucidated. 4,5 Three types of HDAC proteins have been recognized in plants, RPD3-like, SIRT, and HD-tuins. 6 The Arabidopsis genome encodes 18 genes that belong to three HDAC families: 12 RPD3-like family proteins; 2 sirtuin family proteins; and 4 HD-tuin family proteins.…”

mentioning

confidence: 99%

Versatility of HDA19-deficiency in increasing the tolerance of Arabidopsis to different environmental stresses

Ueda

Matsui

Nakamura

et al. 2018

Plant Signaling & Behavior

View full text Add to dashboard Cite

show abstract

Plant Responses to Abiotic Stress Regulated by Histone Deacetylases

Cited by 86 publications

References 64 publications

Transcriptional and Post-Transcriptional Regulation and Transcriptional Memory of Chromatin Regulators in Response to Low Temperature

Transcriptional and Post-Transcriptional Regulation and Transcriptional Memory of Chromatin Regulators in Response to Low Temperature

Arabidopsis histone deacetylase HDA15 directly represses plant response to elevated ambient temperature

Versatility of HDA19-deficiency in increasing the tolerance of Arabidopsis to different environmental stresses

Contact Info

Product

Resources

About