Plantes, médicaments et génétique

Faye, Loı̈c; Champey, Yves

doi:10.1051/medsci/20082411939

Cited by 5 publications

(2 citation statements)

References 10 publications

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“…Consequently, traditional pharmacopeia constitute a guide that is invaluable for modern pharmacological research. Using plant derivatives as medicines has allowed researchers to extract, isolate, and purify biomolecules that are efficacious against several diseases (Faye et al, 2008). In the 1980s, docetaxel extracted from Taxus baccata was used to treatof numerous cancers.…”

Section: Introductionmentioning

confidence: 99%

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Ethnobotanical investigation of medicinal and aromatic plants used in the traditional treatment of COVID-19 in the rural commune of Bni Hadifa, province of Al Hoceima (Central Rif, Northern Morocco)

Jahjah,

Ait Alla,

Erbiai

et al. 2024

Multidiscip. Sci. J.

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This ethnobotanical investigation was conducted in the rural commune of Bni Hadifa belonging to the Al Hoceima province (North of Morocco), to inventory the principal medicinal plants traditionally used to treat Covid-19. Ethnobotanical information was recorded from 84 inhabitants aged over 18 years in the different communes of the study area, using an ethnobotanical survey based on a questionnaire and semistructured interviews. Data were examined by surveying the relative citation frequency (RFC) and family importance value (FIV). The obtained results permitted the inventory of 40 aromatic and medicinal plants (MAPs) species owned by 20 families, the most important of which by their number of species were: Lamiaceae (12 species), Apiaceae (5 species), Asteraceae (3 species), and two species for each of Amaryllidaceae, Myrtaceae, and Rutaceae. Furthermore, the following species: Allium sativum, Thymus glandulosus, Lavandula dentata L, Citrus limon L, Eucalyptus globulus labill, Artemisia herba-alba, and Marrubium vulgare L were the most frequently cited by the RFC index. Leaves were found to be the common plant organ used to treat Covid-19, while decoction was the most frequent preparation mode. This study also showed that over 90% of the respondents proved the efficacy of the plants used against Covid-19. However, most of the users of these plants did not respect the administered doses and were unaware of the toxicity and lethal effects that could be caused by these plants when taking high doses. The results of this survey demonstrate that the plants used to combat Covid-19 may constitute a promising database for future research in the extraction and chemical analysis of potentially effective biomolecules against this virus.

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Section: Introductionmentioning

confidence: 99%

“…In the 1980s, docetaxel extracted from Taxus baccata was used to treatof numerous cancers. Similarly, shikimic acid extracted from green anise seeds (Pimpinella anisum L.) has given rise to oseltamivir, one of the few drugs with proven efficacy in treating influenza (Faye et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Ethnobotanical investigation of medicinal and aromatic plants used in the traditional treatment of COVID-19 in the rural commune of Bni Hadifa, province of Al Hoceima (Central Rif, Northern Morocco)

Jahjah,

Ait Alla,

Erbiai

et al. 2024

Multidiscip. Sci. J.

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Biocatalysis, Enzyme Engineering and Biotechnology

Kotzia

Platis

Axarli

et al. 2012

Food Biochemistry and Food Processing

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Enzymes are biocatalysts evolved in nature to achieve the speed and coordination of nearly all the chemical reactions that define cellular metabolism necessary to develop and maintain life. The application of biocatalysis is growing rapidly, since enzymes offer potential for many exciting applications in industry. The advent of whole genome sequencing projects enabled new approaches for biocatalyst development, based on specialised methods for enzyme heterologous expression and engineering. The engineering of enzymes with altered activity, specificity and stability, using sitedirected mutagenesis and directed evolution techniques are now well established. Over the last decade, enzyme immobilisation has become important in industry. New methods and techniques for enzyme immobilisation allow for the reuse of the catalysts and the development of efficient biotechnological processes. This chapter reviews advances in enzyme technology as well as in the techniques and strategies used for enzyme production, engineering and immobilisation and discuss their advantages and disadvantages. HO CH 2 COOH CH NH 2 Negatively charged amino acids Glutamate Glu (E) CH 2 CH 2 HOOC COOH CH NH 2 Aspartate Asn (N) CH 2 COOH HOOC CH NH 2 Positively charged amino acids Arganine Arg (R) CH 2 CH 2 CH 2 HN COOH CH NH 2 C NH NH 2 Lysine Lys (K) H 2 N COOH (CH 2) 4 CH NH 2 Histidine His (H)

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