Plaque distribution and vascular remodeling of ruptured and nonruptured coronary plaques in the same vessel: an intravascular ultrasound study in vivo

Abstract

Intravascular ultrasound assessment of plaque distribution and vascular remodeling may help to classify plaques with the highest probability of spontaneous rupture.

Study of the Predictors and Lesion Characteristics of Ischemic Heart Disease Patients With False Negative Results in Stress Myocardial Perfusion Single-Photon Emission Tomography

“…Positive remodeling was seen in 4 patients, but there was no clear difference here from frequencies previously reported for angina pectoris patients. [9][10][11][12] For greater clarification of lesion background characteristics of patients in the present study, it would have been preferable to conduct a comparative investigation with lesion backgrounds of patients testing positive in stress perfusion SPECT, but this was not undertaken here. In past Circulation Journal Vol.70, March 2006 investigations of IVUS findings in patients testing positive in stress perfusion SPECT, 13 the mean percentage area stenosis was 78.0±12.2%, revealing no difference with the results of our current study.…”

Intravascular Ultrasound Assessment of Ulcerated Ruptured Plaques

“…An ulcerated ruptured plaque contained a cavity that communicated with the lumen with an overlying residual fibrous cap fragment ( Figure 1). 8 A fissure without a cavity communicating with the true lumen was not included. 5,8 Rupture sites separated by a length of artery containing smooth lumen contours and no cavity were considered to represent different plaque ruptures.…”

“…8 A fissure without a cavity communicating with the true lumen was not included. 5,8 Rupture sites separated by a length of artery containing smooth lumen contours and no cavity were considered to represent different plaque ruptures. Thrombus was an intraluminal mass having a layered or lobulated appearance, evidence of blood flow (microchannels) within the mass, and speckling or scintillation.…”

Clinical Applications of Intravascular Ultrasound

“…These plaques had histological features similar to vulnerable plaques and were associated with increased risk of instability. In addition, IVUS can also identify vulnerable plaques at high risk of rupture in vessels with adaptive remodelling (von Birgelen, Klinkhart et al 2001). IVUS has excellent blood penetration and in the absence of calcium is able to visualize and calculate plaque area, volume and eccentricity.…”