Plasma cell balanitis of Zoon: response to Trimovate                cream

Tang, Alan; David, Nelson; Horton, L. W. L.

doi:10.1258/0956462011916811

Cited by 41 publications

(21 citation statements)

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“…A series of patients treated by a single provider are uncommon, as most reports of BCP are individual cases [15]. Previously, first-line therapy has been circumcision, since the absence of foreskin removes a nidus of chronic inflammation [16, 17].…”

Section: Discussionmentioning

confidence: 99%

Successful Management of Zoon’s Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris

Bari

Cohen

2017

Dermatol Ther (Heidelb)

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IntroductionZoon’s balanitis, also referred to as balanitis circumscripta plasmacellularis (BCP), is an idiopathic, benign inflammatory condition of the glans penis and foreskin most often seen in elderly uncircumcised men. A patient with a biopsy-confirmed diagnosis of BCP who was successfully treated with topical mupirocin ointment is described.MethodsThe PubMed database was searched with the key words: bactroban, balanitis, cell, circumscripta, mupirocin, plasma, plasmacellularis, tacrolimus, Zoon. The papers generated by the search and their references were reviewed.ResultsTreatments for BCP have previously included circumcision and topical calcineurin inhibitors. Our patient with BCP rapidly resolved after initiating treatment with mupirocin 2% ointment.ConclusionBCP is a benign dermatosis affecting the glans penis and foreskin. We confirm an earlier observation demonstrating successful management of this condition with topical mupirocin 2% ointment. Previously reported therapies include circumcision, topical calcineurin inhibitors, phototherapy, and laser therapy. However, based on our observations, topical mupirocin 2% ointment therapy may be considered for the initial management of patients with suspected BCP. Prompt response to mupirocin 2% ointment is highly suggestive of the diagnosis of BCP since morphologically similar skin conditions do not respond to this treatment.

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Section: Discussionmentioning

confidence: 99%

Successful Management of Zoon’s Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris

Bari

Cohen

2017

Dermatol Ther (Heidelb)

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“…3,9 A possible explanation for this tendency may be that subpreputial sac serves as an ideal growth environment for the putative micro-organisms in this entity. 7 Although both the clinical and histopathologic features in our patient were consistent with ZB, the fact that the patient was circumcised led us to the idea that circumcision procedure might have been inadequately performed in this patient. The observation that persistent balanitis developed at sulcus coronarius still covered by the foreskin as a result of inadequate circumcision in patients with ZB provides support for this hypothesis.…”

mentioning

confidence: 59%

Zoon's balanitis in a circumcised man

Toker

Başkan

Tunali

et al. 2007

Journal of the American Academy of Dermatology

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“…[27] and another by Tang et al .,[2] who had highlighted the importance of topical steroids in ZB. According to these studies, moderately potent steroid preparation with or without topical antibiotics is effective alternative to surgical management although these studies did not raise the level of evidence [Table 2]…”

Section: Diagnosismentioning

confidence: 99%

“…[1] It has been described as rare by the textbooks and literature, but probably it is underdiagnosed. [2] Analogous lesions have been described in females with similar clinical and histological features of ZB and termed as Zoon's vulvitis, plasma cell vulvitis, or vulvitis circumscripta plasmacellularis. [1]…”

Section: Introductionmentioning

confidence: 98%

Zoon balanitis: A comprehensive review

Dayal

Sahu

2016

Indian J Sex Transm Dis

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The diagnosis and management of nonvenereal diseases are always a tough challenge for the dermatologist due to lack of studies on its diagnostic criteria and standard treatment guidelines. Zoon balanitis (ZB) is one of the benign nonvenereal dermatoses, which presents as a solitary, persistent erythematous plaque usually on the glans penis primarily in the uncircumcised, middle-aged to old-aged men. Although it was described by Zoon in 1952, its etiopathogenesis still remains hypothetical. This article provides an overview of the epidemiology, clinical presentation, histopathological features, and diagnostic criteria and diagnostic methods of ZB. In addition to this, it is rather very important to differentiate this lesion from its clinical equivocal lesions such as erythroplasia of Queyrat, infective and other inflammatory penile dermatoses, which has been discussed in this review. The treatment modalities have also been reviewed in details, and the importance of circumcision as the treatment of choice has been emphasized.

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Plasma cell balanitis of Zoon: response to Trimovate cream

Cited by 41 publications

References 0 publications

Successful Management of Zoon’s Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris

Successful Management of Zoon’s Balanitis with Topical Mupirocin Ointment: A Case Report and Literature Review of Mupirocin-Responsive Balanitis Circumscripta Plasmacelluaris

Zoon's balanitis in a circumcised man

Zoon balanitis: A comprehensive review

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