Plasma cell tumors of the skull

Multiple myeloma presenting as solitary mass in the posterior fossa

“…2,7 We reviewed case reports and series that included patients with occipital gangliogliomas, excluding studies that did not report patient age. [8][9][10]5,[11][12][13][14][15][16][17][18] We found 22 such patients with occipital ganglioglioma (Table 1): 15 patients 20 years of age or younger, four patients 21 to 30 years old, and only three patients older than 30 years, two of whom had long-standing seizures, suggesting that the tumor arose during the second or third decade of life. Indeed, seizures, affecting more than 90% of ganglioglioma patients, are typically long-standing, 19,6,4 suggesting childhood onset even in adult patients.…”

“…9,13,14 These tumors are considered to be very radiosensitive, and some authors have reported complete response with biopsy followed by radiation for solitary plasmacytomas. [15][16][17] In contrast, there are reports of patients who have undergone gross total resection, without postoperative radiation, and been free of recurrence.…”

Plasmocytoma of the skull vault

“…The occurrence of these symptoms most probably originates from frontal and/or limbic release or disinhibition (5). On the other hand Pringle et al (1999) showed that patients with a meningioma had higher levels of anxiety and depression than those with any other tumour types (8). Although the mass was located extraaxially in our patient, this frontal lesion may have caused amnesia, and irritability by its mass effect preoperatively; and furthermore in the postoperative period these symptoms might have been aggravated by frontal and/ or limbic release or by increased frontal blood flow due to metabolic processes in this area; and finally he had worse mood than before which could have caused his suicide.…”

Solitary Plasmocytoma of the Vault

“…Total surgical resection followed by adjunctive radiationtherapy has been advocated as an effective treatment in the majority of skull plasmacytomas [11]. Our patient underwent surgery with complete resection of tumor (Figure 2).…”