Plasma Cortisol Levels of Dogs at a County Animal Shelter

Hennessy, Michael B.; Davis, Harry N.; Williams, Michael T.; Mellott, Carolyn; Douglas, Chet W

doi:10.1016/s0031-9384(97)80328-9

Cited by 236 publications

(151 citation statements)

References 21 publications

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“…Rates of alarm calling and retreat into nest boxes in response to humans decline quickly during the first 10 d, and the behaviors of animals do not change significantly after this time (J. M. Mateo and S. A. Cavigelli, personal observation). Furthermore, in other species, glucocorticoid concentrations increase after animals are placed in captive housing or transferred to a different housing environment, but the levels return to baseline within 10 d (Hansen and Damgaard 1993;Manzo et al 1994;Hennessy et al 1997). Based on these observations we expected that the stress induced by captivity would be attenuated before the study started, with little change thereafter.…”

Section: Study 2: Relationship Between Basal Concentrations Of Serum mentioning

confidence: 99%

A Validation of Extraction Methods for Noninvasive Sampling of Glucocorticoids in Free‐Living Ground Squirrels

Mateo

Cavigelli

2005

Physiological and Biochemical Zoology

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Fecal hormone assays provide a powerful tool for noninvasive monitoring of endocrine status in wild animals. In this study we validated a protocol for extracting and measuring glucocorticoids in freeliving and captive Belding's ground squirrels (Spermophilus beldingi). We first compared two commonly used extraction protocols to determine which performed better with commercially available antibodies. We next verified the preferred extraction method by correlating circulating and fecal glucocorticoid measures from a group of individuals over time. For this comparison, we used both a cortisol and a corticosterone antibody to determine which had greater affinity to the fecal metabolites. Cortisol was the primary circulating glucocorticoid, but both hormones were present in well above detectable concentrations in the blood, which does not occur in other sciurids. In addition, the cortisol antibody showed greater binding with the fecal extracts than did the corticosterone antibody. Finally, we used adrenocorticotropic hormone and dexamethasone challenges to demonstrate that changes in adrenal functioning are reflected in changing fecal corticoid levels. These results suggest that our extraction protocol provides a fast, reliable assay of stress hormones in freeliving ground squirrels without the confounding influence of short-term rises in glucocorticoid concentrations caused by handling and restraint stress and that it can facilitate ecological and evolutionary studies of stress in wild species.

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Section: Study 2: Relationship Between Basal Concentrations Of Serum mentioning

confidence: 99%

A Validation of Extraction Methods for Noninvasive Sampling of Glucocorticoids in Free‐Living Ground Squirrels

Mateo

Cavigelli

2005

Physiological and Biochemical Zoology

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“…For dogs in rescue centres, the situation is further compounded by the fact that many have been separated from their owners [46] and can be in poor physical condition having been neglected and/or abused. Previous studies have shown that a physiological stress response is stimulated on arrival at a kennel and can remain activated for days [19] or even weeks [42]. Rescue dogs can remain in kennels for several months and in some cases, years and if they fail to adapt to these conditions they are at risk of becoming chronically stressed.…”

Section: Introductionmentioning

confidence: 99%

‘The effect of different genres of music on the stress levels of kennelled dogs’

Bowman

Dowell

Evans

2017

Physiology & Behavior

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“…In the previous studies, in addition to serum cortisol elevation, hyperactivity of HPA axis, the main mammalian system of stress response [6] , was confirmed by increased corticotropin-releasing hormone levels in cerebrospinal fluid [40] and increased urinary cortisol levels in patients with OCD [41] . Elevated serum cortisol has been accepted as a physiological marker of stress and behavior abnormalities, particularly for dogs in animal shelter, as well [42] .…”

Section: Discussionmentioning

confidence: 99%

Kompulsif Kuyruk Isıran Köpeklerin Serum Leptin ve Ghrelin Seviyeleri ve Serum Kortizol, Tiroid Hormonları, Lipidler, Homosistein ve Folik Asit İle İlişkileri

Yalçın¹,

Yılmaz²,

Özarda³

2017

Kafkas Univ Vet Fak Derg

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Citation of This ArticleYalcın E, Yilmaz Z, Ozarda Y: Serum leptin and ghrelin levels and their relationship with serum cortisol, thyroid hormones, lipids, homocysteine and folic acid in dogs with compulsive tail chasing. Kafkas Univ Vet Fak Derg, 23 (2): 227-232, 2017. DOI: 10.9775/kvfd.2016 AbstractThe aim of this study was to investigate serum leptin and ghrelin levels and their relations with circulating cortisol, thyroid hormones, lipids, homocysteine (Hcy) and folic acid in dogs with compulsive tail chasing (CTC). The material of this study consists of fifteen dogs with CTC and 15 healthy controls of various weights, breeds, ages of both sexes were enrolled in the study. CTC was diagnosed on the basis of the dog's behavioral history, clinical signs, and results of other medical assessments. None of the dogs were considered to have concurrent medical disease that would account for CTC. Dogs with CTC had a higher leptin (8.3±0.9 ng/mL vs 1.7±0.2 ng/mL, P<0.001) and lower ghrelin levels (74±7 pg/mL vs 144±41 pg/mL, P<0.05) than those of healthy controls. Serum cortisol, lipids (cholesterol, phospholipids and NEFA) and Hcy levels increased (P<0.05), whereas serum folic acid decreased (P<0.001) in dogs with CTC as compared with controls. Serum ghrelin correlated negatively with cholesterol (P<0.05), but serum leptin correlated positively with cholesterol, fT4, and phospholipids (P<0.05). These results suggest that serum leptin and ghrelin levels may bring up a new perspective on our understanding of the pathophysiological mechanisms associated with CTC. Serum levels of both hormones may be associated with serum levels of lipids and free T4. Keywords

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Plasma Cortisol Levels of Dogs at a County Animal Shelter

Cited by 236 publications

References 21 publications

A Validation of Extraction Methods for Noninvasive Sampling of Glucocorticoids in Free‐Living Ground Squirrels

A Validation of Extraction Methods for Noninvasive Sampling of Glucocorticoids in Free‐Living Ground Squirrels

‘The effect of different genres of music on the stress levels of kennelled dogs’

Kompulsif Kuyruk Isıran Köpeklerin Serum Leptin ve Ghrelin Seviyeleri ve Serum Kortizol, Tiroid Hormonları, Lipidler, Homosistein ve Folik Asit İle İlişkileri

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