Plasma dehydroepiandrosterone‐to‐cortisol ratios as an indicator of stress in gynecologic patients

Effects of dehydroepiandrosterone-sulfate (DHEA-S) and benznidazole treatments during acute infection of two different Trypanosoma cruzi strains

“…In humans, DHEA-S concentrations in blood, urine, saliva and cerebrospinal fluid decline with aging as well as with inflammation (Chen and Parker 2004) and many causing some illnesses (Parker et al 1985;Ozasa et al 1990;Nishikaze 1998;Spratt et al 1993. It is not known whether these age-and illness-related declines are pathophysiologically related to the manifestations of aging and of illness.…”

Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS)

“…In humans, DHEA(S) concentrations in blood, urine, saliva, and cerebrospinal fluid (CSF) decline with aging as well as with chronic and sub-chronic stress [107; 115; 232], inflammation [61] and many medical illnesses [80; 225; 232; 235; 293]. It is not known whether these age- and illness-related declines are pathophysiologically related to the manifestations of aging and of illness.…”

Affectionate Communication Received from Spouses Predicts Stress Hormone Levels in Healthy Adults

“…When mathematically expressed as cortisol divided by DHEA-S (rather than the obverse), CDR should show direct associations with stress, since stress increases levels of the numerator (cortisol) and decreases levels of the denominator (DHEA-S) (see Parker, Levin, & Lifrak, 1985). Previous investigations have demonstrated that CDR is directly associated with multiple diverse forms of stress, including surgical stress (Ozasa, Kita, Inoue, & Mori, 1990), bodily stress due to anorexia nervosa (Zumoff et al, 1983) or injury (Butcher, Killampalli, Lascelles, Wang, Alpar, & Lord, 2005), laboratory induced stress (Whetzel et al, 2006) or fear (Grillon, Pine, Baas, Lawley, Ellis, & Charney, 2005), and the stress of military school (Morgan et al, 2004), and can be significantly decreased by a cognitivebehavioral stress management intervention (Cruess et al, 1999).…”