2023
DOI: 10.1002/dad2.12461
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Plasma‐derived biomarkers of Alzheimer's disease and neuropsychiatric symptoms: A community‐based study

Janina Krell‐Roesch,
Isabella Zaniletti,
Jeremy A. Syrjanen
et al.

Abstract: INTRODUCTIONWe examined associations between plasma‐derived biomarkers of Alzheimer's disease (AD) and neuropsychiatric symptoms (NPS) in community‐dwelling older adults.METHODSCross‐sectional study involving 1005 persons ≥50 years of age (mean 74 years, 564 male, 118 cognitively impaired), who completed plasma‐derived biomarker (amyloid beta 42 [Aβ42]/Aβ40, phosphorylated tau 181 [p‐tau181], p‐tau217, total tau [t‐tau], neurofilament light [NfL]), and NPS assessment.RESULTSP‐tau181 (odds ratio [OR] 2.06, 95% … Show more

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