2022
DOI: 10.21203/rs.3.rs-1704637/v1
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Plasma derived phosphoglycerate mutase 5 (PGAM5) as a biomarker for Parkinson’s disease

Abstract: Background: Phosphoglycerate mutase 5 (PGAM5) regulates mitochondrial dynamics and programmed cell death, which relates to the pathogenesis of Parkinson’s disease (PD). This study aimed to examine whether plasma PGAM5 was a biomarker for PD diagnosis, and whether which was associated with the severity of motor or nonmotor manifestations of PD.Methods: Our data enrolled 124 patients of PD (PD group) and 50 healthy controls (HC group) , baseline characteristics of both groups were collected. We measured plasma P… Show more

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