Abstract:Background: In patients presenting with acute liver failure (ALF) prediction of prognosis is vital to determine the need of transplantation. Based on the evidence that plasma disappearance rate of indocyanine green (ICG-PDR) correlates with liver cell function, we evaluated the ability of ICG-PDR measured by pulse dye densitometry to predict outcome in patients with acute liver failure. Methods: Prospectively markers of hepatocellular injury, synthesis and excretion, including ICG-PDR were measured daily until… Show more
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