1977
DOI: 10.1002/bjs.1800640705
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Plasma gastrin concentration related to acid secretion during insulin hypoglycaemia

Abstract: The release of gastrin by insulin hypoglycaemia was studied in man before and after vagotomy. Completeness of vagotomy was judged by the gastric acid response to the same hypoglycaemia, using several criteria including one that allows for pyloric losses and duodenogastric reflux. A total of 137 tests was performed on 10 subjects. The plasma gastrin concentration was found to rise in the preoperative studies and also in the postoperative studies no matter what type of vagotomy had been performed or what criteri… Show more

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“…The specimens were collected in heparin bottles, centrifuged, and the plasma separated for gastrin measurement by radioimmunoassay following the method described by Russell et al (1977), the concentrations being expressed as pg/ml.…”
Section: Subjectsmentioning
confidence: 99%
“…The specimens were collected in heparin bottles, centrifuged, and the plasma separated for gastrin measurement by radioimmunoassay following the method described by Russell et al (1977), the concentrations being expressed as pg/ml.…”
Section: Subjectsmentioning
confidence: 99%
“…9 The control mechanisms for gastrin release are complex, with stimulatory and inhibitory components. Investigation of gastrin responses in patients with chronic autonomic failure might elucidate the role of the autonomic nervous system in regulating gastrin secretion.…”
mentioning
confidence: 99%