Plasma Glutamine Responses to High-Intensity Exercise Before and After Endurance Training

Kargotich, Stephen; Goodman, Carmél; Dawson, Brian; Morton, Alan R.; Keast, David; Joske, David

doi:10.1080/15438620500359729

Cited by 15 publications

(4 citation statements)

References 28 publications

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“…Glutamine concentration in plasma may decline after intense long-term exercise (Castell et al 1997;Kargotich et al 2005). Intense exercise decreases neutrophil function and enhances the susceptibility to infection (Pyne et al 1995).…”

Section: Treinability Indicatorsmentioning

confidence: 99%

Exercise training raises expression of the cytosolic components of NADPH oxidase in rat neutrophils

et al. 2007

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Exercise activates neutrophil burst and this effect is dependent on training status and exercise intensity. In this study, the chronic effect of treadmill exercise on phagocytosis, production of reactive oxygen metabolites and expression of NADPH oxidase components in rat neutrophils was investigated. Neutrophils were obtained by intraperitoneal lavage with PBS. After 11 weeks of training the exercised group showed increased phagocytosis capacity (49%) and production of reactive oxygen metabolites (6.6-fold) when compared with neutrophils from the sedentary group. Exercised had no effect on expression of the membrane components of NADPH oxidase (p22( phox ), gp91( phox )). In contrast, there was an increase of the p47( phox ) mRNA levels (by 126%), the cytosolic component of the enzyme. In addition, exercise increased the protein content of p47( phox ) (by 22%) and of p67( phox ) (by 2.8-fold) in neutrophils. Evidence is then presented that training to moderate exercise increases phagocytosis and production of reactive oxygen metabolites and the expression of p47( phox ) and p67( phox ) in neutrophils. Therefore, moderate exercise might enable neutrophils to respond more efficiently when exposed to pathogens.

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Section: Treinability Indicatorsmentioning

confidence: 99%

Exercise training raises expression of the cytosolic components of NADPH oxidase in rat neutrophils

et al. 2007

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“…Serum concentrations of glutamine generally fall after exercise, reflecting conversion of glutamine to glutamate. Nonetheless, it is accepted that baseline levels of glutamine will increase over time as the result of a progressive training program [11,12]. Additionally, significant variance in resting glutamine levels can be seen between athletes of different sports.…”

Section: General Exercise Effectsmentioning

confidence: 99%

Glutamine

Phillips¹

2007

Current Sports Medicine Reports

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Glutamine is a popular dietary supplement consumed for purported ergogenic benefits of increased strength, quicker recovery, decreased frequency of respiratory infections, and prevention of overtraining. From a biochemical standpoint, glutamine does play a physiologic role in each of these areas, but it remains only one of a host of factors involved. This review examines the effects of glutamine on exercise and demonstrates a lack of evidence for definitive positive ergogenic benefits as a result of glutamine supplementation.

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“…Plasma glutamine concentrations decreased significantly in runners who participated in 9-9.5 days of twice-a-day interval training [31]. Recreationally active males demonstrated significantly decreased glutamine concentrations following strenuous interval training sessions [32]. Reduced glutamine levels are responsible for the immune suppression associated with increased infection rates observed in overtrained athletes [33].…”

Section: Introductionmentioning

confidence: 99%

Concurrent Ingestion of Alkaline Water and L-Glutamine Enhanced Salivary α-Amylase Activity and Testosterone Concentration in Boxing Athletes

Lu,

He,

Suzuki

et al. 2024

Nutrients

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Athletes often take sport supplements to reduce fatigue and immune disturbances during or after training. This study evaluated the acute effects of concurrent ingestion of alkaline water and L-glutamine on the salivary immunity and hormone responses of boxers after training. Twelve male boxing athletes were recruited in this study. During regular training, the participants were randomly divided into three groups and asked to consume 400 mL of alkaline water (Group A), 0.15 g/kg body weight of L-glutamine with 400 mL of water (Group G), and 0.15 g/kg of L-glutamine with 400 mL of alkaline water (Group A+G) at the same time each day for three consecutive weeks. Before and immediately after the training, saliva, heart rates, and the rate of perceived exertion were investigated. The activity of α-amylase and concentrations of lactoferrin, immunoglobulin A (IgA), testosterone, and cortisol in saliva were measured. The results showed that the ratio of α-amylase activity/total protein (TP) significantly increased after training in Group A+G but not in Group A or G, whereas the ratios of lactoferrin/TP and IgA/TP were unaffected in all three groups. The concentrations of salivary testosterone after training increased significantly in Group A+G but not in Group A or G, whereas the salivary cortisol concentrations were unaltered in all groups. In conclusion, concurrent ingestion of 400 mL of alkaline water and 0.15 g/kg of L-glutamine before training enhanced the salivary α-amylase activity and testosterone concentration of boxers, which would be beneficial for post-exercise recovery.

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Plasma Glutamine Responses to High-Intensity Exercise Before and After Endurance Training

Cited by 15 publications

References 28 publications

Exercise training raises expression of the cytosolic components of NADPH oxidase in rat neutrophils

Exercise training raises expression of the cytosolic components of NADPH oxidase in rat neutrophils

Glutamine

Concurrent Ingestion of Alkaline Water and L-Glutamine Enhanced Salivary α-Amylase Activity and Testosterone Concentration in Boxing Athletes

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