Plasma histamine levels during the first week of life.

Cooper, L. V.; Harvey, David; Davis, JohnA.

doi:10.1136/adc.44.236.487

Cited by 2 publications

(3 citation statements)

References 12 publications

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“…The German workers gave no details of the methods they used for the partitioning of the blood, but if specimens are stored for prolonged periods at room temperature there can be breakdown of the cells resulting in falsely low counts. The distribution of eosinophils found here was skew and a similar distribution was reported by Cooper, Harvey & Davis (1969).…”

Section: Discussionsupporting

confidence: 90%

“…Their high plasma levels may have been due to the techniques they used: it is thought that the histamine-containing cells (basophils) may be more fragile than normal at birth and these workers gave few details of their methods of collection and plasma separation. Cooper et al (1969) found small amounts of histamine in the plasma of healthy " term" newborn infants. Their specimens were obtained by heel pricks and the histamine estimated spectrophotofluorimetrically.…”

Section: Discussionmentioning

confidence: 91%

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Histamine and granulocytes in the umbilical cord blood of infants at birth

Mitchell

Porter

1970

British J Pharmacology

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Summary Histamine levels in whole blood and plasma from the umbilical arteries and veins, together with circulating basophil and eosinophil counts, were determined in two groups of healthy infants, “term” and “pre‐term”. No significant arteriovenous differences were found except in the basophil counts of the “pre‐term” group. This result was consistent with the finding of significant arteriovenous correlations for all these sets of estimations except the basophil counts in the “pre‐term” group. No significant differences were found between the mean values in either group except for the difference between the mean basophil counts for venous blood. Plasma histamine levels (arterial and venous) were usually less than the lowest limit of the method (1.8 ng/ml). Very small amounts of histamine were detected, however, in one venous and one arterial specimen in the “pre‐term” group, but these did not produce a significant difference between the levels for the two groups of infants.

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