The field of plasma-induced ignition and plasmaassisted combustion in high-speed flow is under consideration. Nonequilibrium, unsteady, and nonuniform modes are analyzed as the most promising in reducing a required extra power. Numerical simulations of uniform, nonequilibrium, continuous, and pulse discharge effect on the premixed hydrogen and ethylene-air mixtures in supersonic flow demonstrate an advantage of such a technique over heating. At the same time, the energetic price occurs rather large to be scheme practical. A reduction of the required power deposition and mixing intensification in nonpremixed flow could be achieved by nonuniform electrical discharges. Experimental results on multielectrode discharge maintenance behind wallstep and in the cavity of supersonic flow are presented. The model test on hydrogen and ethylene ignition is demonstrated at direct fuel injection.