Plasma Levels of Adrenocorticotropic Hormone and Cortisol in People Living in an Environment Below Sea Level (Jordan Valley) during Fasting in the Month of Ramadan

El-Migdadi, Fayig; El-Akawi, Zeyad; Abudheese, Rola; Bashir, Nabil

doi:10.1159/000066446

Cited by 11 publications

(5 citation statements)

References 10 publications

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“…Moreover, the nocturnal increase [59][60][61] and the diurnal decrease in cortisol serum levels [59,61,62] suggest that the amplitude of cortisol rhythm is also decreased. An increase in the cortisol level at 15: 00 h was also reported in a recent study where blood sampling was carried out at that point only [63] .…”

Section: Circadian and Hormonal Changes During Ramadansupporting

confidence: 82%

Physiological and Chronobiological Changes during Ramadan Intermittent Fasting

et al. 2004

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Background and Aims: During the month of Ramadan, Moslems refrain from drinking and eating between sunrise and sunset. This review aimed to analyze the effects of Ramadan fasting on physiological and behavioral variables in healthy subjects. Methods: Articles included in this paper were taken from Medline, three international congresses on health and Ramadan, and in several cases from local journals. Results: Ramadan fasting did not dramatically affect the metabolism of lipids, carbohydrates and proteins, or the daily mean of hormonal serum levels. An increase in serum urea and uric acid was frequently reported and this could be attributed to dehydration during this month. Some changes, such as the increase of HDL and apoprotein A1, and the decrease in LDL, could be beneficial for the cardiovascular system. However, the chronobiological studies have shown that Ramadan fasting affects the circadian distribution of body temperature, cortisol, melatonin and glycemia. The amplitude of most of these rhythms decreased and the acrophase shifted. Nocturnal sleep, daytime alertness and psychomotor performance were decreased. Conclusion: The major changes during Ramadan fasting are chronobiological and behavioral. They could be responsible for the high incidence of road traffic accidents and the reduction of working hours during the month of Ramadan.

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Section: Circadian and Hormonal Changes During Ramadansupporting

confidence: 82%

Physiological and Chronobiological Changes during Ramadan Intermittent Fasting

et al. 2004

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“…Literature data suggest that Ramadan decreases the amplitude of the cortisol circadian rhythm by increasing its nocturnal levels while decreasing its diurnal circulating levels ( 161 – 163 ). A serum cortisol increase at 3:00 p.m. can occur in Ramadan ( 164 ). During Ramadan, although still within the normal reference ranges, immune cells can also significantly decrease, as well as proinflammatory cytokines and chemokines levels, with consequences, e.g., cancer-associated processes ( 165 , 166 ).…”

Section: Involvement Of Steroid Hormones In Dietary Interventionsmentioning

confidence: 99%

The Role of Steroid Hormones in the Modulation of Neuroinflammation by Dietary Interventions

et al. 2016

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Steroid hormones, such as sex hormones and glucocorticoids, have been demonstrated to play a role in different cellular processes in the central nervous system, ranging from neurodevelopment to neurodegeneration. Environmental factors, such as calorie intake or fasting frequency, may also impact on such processes, indicating the importance of external factors in the development and preservation of a healthy brain. The hypothalamic–pituitary–adrenal axis and glucocorticoid activity play a role in neurodegenerative processes, including in disorders such as in Alzheimer’s and Parkinson’s diseases. Sex hormones have also been shown to modulate cognitive functioning. Inflammation is a common feature in neurodegenerative disorders, and sex hormones/glucocorticoids can act to regulate inflammatory processes. Intermittent fasting can protect the brain against cognitive decline that is induced by an inflammatory stimulus. On the other hand, obesity increases susceptibility to inflammation, while metabolic syndromes, such as diabetes, are associated with neurodegeneration. Consequently, given that gonadal and/or adrenal steroids may significantly impact the pathophysiology of neurodegeneration, via their effect on inflammatory processes, this review focuses on how environmental factors, such as calorie intake and intermittent fasting, acting through their modulation of steroid hormones, impact on inflammation that contributes to cognitive and neurodegenerative processes.

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“…Although this phenomenon has not been directly studied in fishes, there is indirect support for a relationship between stress hormones and leptin. Fasting increases cortisol in mammals (Chang et al, 2002; El-Migdadi et al, 2002). In fish, fasting can increase cortisol (Kelley et al, 2001; Barcellos et al, 2010), have no effect (Sumpter et al, 1991; Pottinger et al, 2003) or even result in decreased plasma cortisol (Small, 2005).…”

Section: What Aspects Of Leptin Function Are Conserved Between Fish Amentioning

confidence: 99%

Leptin in Teleost Fishes: An Argument for Comparative Study

Copeland¹,

Duff²,

Liu³

et al. 2011

Front. Physio.

101

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All organisms face tradeoffs with regard to how limited energy resources should be invested. When is it most favorable to grow, to reproduce, how much lipid should be allocated to storage in preparation for a period of limited resources (e.g., winter), instead of being used for growth or maturation? These are a few of the high consequence fitness “decisions” that represent the balance between energy acquisition and allocation. Indeed, for animals to make favorable decisions about when to grow, eat, or reproduce, they must integrate signals among the systems responsible for energy acquisition, storage, and demand. We make the argument that leptin signaling is a likely candidate for an integrating system. Great progress has been made understanding the leptin system in mammals, however our understanding in fishes has been hampered by difficulty in cloning fish orthologs of mammalian proteins and (we assert), underutilization of the comparative approach.

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Plasma Levels of Adrenocorticotropic Hormone and Cortisol in People Living in an Environment Below Sea Level (Jordan Valley) during Fasting in the Month of Ramadan

Cited by 11 publications

References 10 publications

Physiological and Chronobiological Changes during Ramadan Intermittent Fasting

Physiological and Chronobiological Changes during Ramadan Intermittent Fasting

The Role of Steroid Hormones in the Modulation of Neuroinflammation by Dietary Interventions

Leptin in Teleost Fishes: An Argument for Comparative Study

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