Plasma levels of insulin-like growth factor-I, insulin-like growth factor binding protein-1, coenzyme Q10 and vitamin E in female populations from Poland, Serbia and Sweden

Tekle, Michael; Gromadzińska, Jolanta; Joksić, Gordana; Antić, Ruza; Nilsson, Robert; Dallner, Gustav; Undén, Anna‐Lena; Brismar, Kerstin

doi:10.1016/j.envint.2009.11.003

Cited by 15 publications

(7 citation statements)

References 31 publications

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“…However, there was no evidence of energy deficiency in these athletes because their levels of IGFBP-1 were in the upper portion of the normal range for healthy Swedish men. 30,36 Although their leptin levels were below the values reported for healthy sedentary men, 37 these values were similar to those observed previously in highly trained athletes. 38 The POMS values for our subjects were comparable with normative values for men among the general population, 7 as well as to the values for a large group of athletes documented by Terry and Lane (2000).…”

Section: Discussionsupporting

confidence: 88%

Body Composition and Endocrine Profile of Male Olympic Athletes Striving for Leanness

Hagmar¹,

Berglund²,

Brismar

et al. 2013

Clinical Journal of Sport Medicine

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Section: Discussionsupporting

confidence: 88%

Body Composition and Endocrine Profile of Male Olympic Athletes Striving for Leanness

Hagmar¹,

Berglund²,

Brismar

et al. 2013

Clinical Journal of Sport Medicine

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“…Our results agree with previous studies in the observation that serum IGF-I levels may be modulated by exogenous factors, such as environmental pollutants [14], [38], [54], [55]. These results agree with some previous reports of our research group showing lower IGF-I serum levels in subjects with higher levels of organochlorine pesticides in a way that is highly influenced by gender, age and the involved chemical or combination of chemicals [14], [33].…”

Section: Discussionsupporting

confidence: 93%

The Relationship between Dioxin-Like Polychlorobiphenyls and IGF-I Serum Levels in Healthy Adults: Evidence from a Cross-Sectional Study

et al. 2012

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ObjectiveInsulin-like growth factor I (IGF-I) and dioxin-like polychlorobiphenyls (DL-PCBs) have been associated with the pathogenesis of several diseases like cancer, diabetes and growth disorders. Because it has been suggested that organohalogenated contaminants could influence IGF-I levels in adults, the potential relationship between DL-PCBs and IGF-I serum levels was studied in 456 healthy adults from a representative sample of the general population of the Canary Islands (Spain).DesignFree circulating serum levels of IGF-I and IGFBP-3 were measured through an ELISA methodology, while the serum levels of the 12 DL-PCBs congeners (IUPAC numbers # 77, 81, 105, 114, 118, 123, 126, 156, 157, 167, 169, and 189) were measured by gas chromatography/mass spectrometry (GC-MS).ResultsDL-PCBs 156 and 167, Total DL-PCBs body burden (∑PCBs: sum over the 12 measured DL-PCBs), and Total toxic burden (in terms of toxic equivalence to dioxins: ∑TEQs) showed a trend of inverse association with IGF-I serum levels in the whole studied population. After adjusting for potential confounders, including gender, body mass index (BMI), age, and IGF-binding protein-3 (IGFBP-3), younger (18–45 years) women with lower BMI (<27 kg/m2) and detectable levels of DL-PCB-156 showed significantly lower IGF-I levels than those in the same age and BMI subgroup with non-detectable levels of DL-PCB-156 (p<0.001). Similarly, ∑PCBs and ∑TEQs showed a tendency to an inverse association with IGF-I levels in the same group of women (p=0.017 and p=0.019 respectively).ConclusionsThese findings suggest that DL-PCBs could be involved in the regulation of the IGF-system in a way possibly influenced by gender, age and BMI. Although these results should be interpreted with caution, such circumstances could contribute to explain the development of diseases associated to the IGF system.

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“…Plasma vitamin E level in vitiligo patients ranged from 5 μg/ml to 18 μg/ml, with average value of 9.3 μg/ml. While average vitamin E level and its range can vary depending on local geosocial conditions [11] and data on population average vitamin E level for Moscow region are not available, current reference values for age group older than 20 years for normal vitamin E level are from 5 μg/ml to 18 μg/ml. Therefore, neither of vitiligo patients has vitamin E deficiency.…”

Section: Resultsmentioning

confidence: 99%

Vitamin E in Vitiligo: Toward Solving the Mystery

Коробко¹,

Lomonosov²

2014

Pigmentary Disorders

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Plasma levels of insulin-like growth factor-I, insulin-like growth factor binding protein-1, coenzyme Q10 and vitamin E in female populations from Poland, Serbia and Sweden

Cited by 15 publications

References 31 publications

Body Composition and Endocrine Profile of Male Olympic Athletes Striving for Leanness

Body Composition and Endocrine Profile of Male Olympic Athletes Striving for Leanness

The Relationship between Dioxin-Like Polychlorobiphenyls and IGF-I Serum Levels in Healthy Adults: Evidence from a Cross-Sectional Study

Vitamin E in Vitiligo: Toward Solving the Mystery

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