2019
DOI: 10.21873/invivo.11570
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Plasma Medicine: A Field of Applied Redox Biology

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Cited by 237 publications
(184 citation statements)
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References 177 publications
(254 reference statements)
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“…[ 5 ] The current indication of medical plasma therapy is to promote beneficial effects on the healing of chronic wounds and ulcers, apart from other dermatological indications. [ 6 ] Strikingly, antitumor efficacy in head and neck cancer patients suggested plasma treatment to have a role in oncology as well. [ 7 ] The concept linking these seemingly unrelated effects of stimulation of healing in non‐healing wounds on the one hand, and killing of tumor cells on the other hand is termed hormesis.…”
Section: Introductionmentioning
confidence: 99%
“…[ 5 ] The current indication of medical plasma therapy is to promote beneficial effects on the healing of chronic wounds and ulcers, apart from other dermatological indications. [ 6 ] Strikingly, antitumor efficacy in head and neck cancer patients suggested plasma treatment to have a role in oncology as well. [ 7 ] The concept linking these seemingly unrelated effects of stimulation of healing in non‐healing wounds on the one hand, and killing of tumor cells on the other hand is termed hormesis.…”
Section: Introductionmentioning
confidence: 99%
“…Cold Atmospheric Plasma (CAP) is an emerging tool of biomedical and clinical importance that controls cellular processes such as wound healing, immunomodulation, cell death, and cancer. CAP is a partially ionized molecular or noble gas or gas mixture that generates a plethora of reactive oxygen and nitrogen species (ROS/RNS), radiation (ultraviolet (UV), visible, and infrared), and small chemical entities such as neutral molecules, ions, electrons, and exited atoms under atmospheric pressure and ambient temperature [1].…”
Section: Introductionmentioning
confidence: 99%
“…Recent reports also indicate that CAP supports wound healing by influencing cell viability [7,8], proliferation [9], migration [10], inflammation [11], dermal regeneration, and reepithelization [12]. Currently, only a small number of studies have examined the cellular and molecular effects of CAP-mediated wound healing [1,13,14] and the mechanisms underlying CAP-mediated wound healing in the context of regenerative pathways require further investigation.…”
Section: Introductionmentioning
confidence: 99%
“…One such innovative procedure, which complements the intraoperative treatment of tumor tissue, could be CAP treatment of the resection margins. The antitumor effects of CAP have already been demonstrated in some cancer entities such as melanoma and pancreatic and breast carcinomas [24][25][26]. Many of the cellular effects, such as reactive oxygen species (ROS) and reactive nitrogen species (RNS) response as products of CAP treatment, have been already described in detail [27].…”
Section: Discussionmentioning
confidence: 99%
“…The antitumor effects of CAP have already been demonstrated in some cancer entities such as melanoma and pancreatic and breast carcinomas [23][24][25]. Many of the cellular effects, such as reactive oxygen species (ROS) and reactive nitrogen species (RNS) response as products of CAP treatment, have been already described in detail [26]. Possible events after CAP treatment triggered by intracellular reactive species, including DNA damage [27], lipid peroxidation [28], or mitochondrial dysfunction [29,30], have also been reported.…”
Section: Discussionmentioning
confidence: 99%