2020
DOI: 10.1016/j.genrep.2019.100563
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Plasma oxidized low-density lipoprotein level and miRNA-146a gene expression, as a strong predictor for atherosclerotic coronary artery disease and its associated response to atorvastatin in a sample of the Iraqi population

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Cited by 5 publications
(4 citation statements)
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“…In the previous of our publication, some demographic characteristics were studied and demonstrated. However, the mean age, gender, weight, height, BMI, SBP, DBP, and drinking habit differed non significantly between the two study groups (P< 0.05; Table 2) [16].…”
Section: Demographic Distribution Of the Study Populationmentioning
confidence: 92%
“…In the previous of our publication, some demographic characteristics were studied and demonstrated. However, the mean age, gender, weight, height, BMI, SBP, DBP, and drinking habit differed non significantly between the two study groups (P< 0.05; Table 2) [16].…”
Section: Demographic Distribution Of the Study Populationmentioning
confidence: 92%
“…The study was ethically approved by the Ministry of Health in Iraq (decree order 3310 on 08/12/2021), through the Scientific Committee of the College of Biotechnology, Al-Nahrain University, carried out between December 2021 and May 2022. Patients diagnosed with ASCAD with TC usually greater than 200mg/dl and LDL-C greater than 160mg/dl (hypercholesterolemia), triglycerides (TG) less than 200 mg/dl whose other lipid levels were normal according to the American heart association (AHA) guidelines, coronary angiography technique should be included with criteria equal to or more than 50 percent stenosis of at least one major coronary vessel due to atherosclerosis and confirmed by two experienced cardiologists ASCAD, and normolipidemic subjects with LDL-C less than 130 mg/dl and TG less than 150 mg/dl 4 . Exclusion criteria were: subjects with the presence of hypertension were previously diagnosed to have hypertension by a clinician.…”
Section: Materials and Proceduresmentioning
confidence: 99%
“…A Receiver Operator Curve (ROC) was used to discover if the study parameter could be predictive of ASCAD 4 . As displayed in Table 5, the serum PCSK9 level in a patient with atherosclerotic coronary artery disease has a high predictor of ASCAD with AUC=0.98, with the best Cutioffivalue = 226.29ng/ml, sensitivity 93.20%, and specificity 100%, and displayed a significant difference P= 0.00.…”
Section: Receiver Operating Characteristic (Roc) Analysis Of Study Pa...mentioning
confidence: 99%
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