Plasma protein expression pattern in congenital analbuminemia – systematic review protocol v1

Abstract

Congenital analbuminemia patients do not express albumin due to genetic mutation. Here a protocol is described for carrying out a systematic review of published case reports on congenital analbuminemia patients. The goal is to assess abundances of a variety of plasma proteins and total plasma protein concentration in this patient population. From the literature search, concentration of individual plasma proteins, plasma protein classes, and total plasma protein concentration is assessed in comparison to reference ranges.